The advancement of single-cell RNA-sequencing technologies has led to an explosion of
cell type definitions across multiple organs and organisms. While standards for data and …

Establishing the molecular diversity of cell types is crucial for the study of the nervous
system. We compiled a cross-laboratory database of mouse brain cell type-specific …

Single-cell studies have delineated cellular diversity and uncovered increasing numbers of
previously uncharacterized cell types in complex tissues. Thus, synthesizing growing …

The ability to spatially resolve the cellular architecture of human cortical cell types over
informative areas is essential to understanding brain function. We combined in situ …

Characterizing cellular diversity at different levels of biological organization and across data
modalities is a prerequisite to understanding the function of cell types in the brain …

To understand the function of cortical circuits, it is necessary to catalog their cellular
diversity. Past attempts to do so using anatomical, physiological or molecular features of …

Single-cell genomics is rapidly advancing our knowledge of the diversity of cell phenotypes,
including both cell types and cell states. Driven by single-cell/-nucleus RNA sequencing …

Highlights•Cell types correspond to self-stabilizing regulatory networks that establish and
maintain a core phenotypic program.•Single cell molecular profiling of transcriptomes and …

Scalable technologies to sequence the transcriptomes and epigenomes of single cells are
transforming our understanding of cell types and cell states. The Brain Research through …

Defining cell types requires integrating diverse single-cell measurements from multiple
experiments and biological contexts. To flexibly model single-cell datasets, we developed …