[HTML][HTML] Transcriptional activation of yeast nucleotide biosynthetic gene ADE4 by GCN4.

HU Mösch, B Scheier, R Lahti, P Mäntsäla… - Journal of Biological …, 1991 - Elsevier
The yeast transcriptional regulator protein GCN4 harbors the bZIP DNA binding motif, which
is common to a family of DNA-binding proteins in eukaryotic organisms from yeast to man …

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeast

IA Hope, K Struhl - Cell, 1986 - Elsevier
Yeast GCN4 protein binds specifically to the promoters of amino acid biosynthetic genes
and coordinately induces their transcription. Serially deleted GCN4 and hybrid LexA-GCN4 …

Two distinct yeast transcriptional activators require the function of the GCN5 protein to promote normal levels of transcription.

T Georgakopoulos, G Thireos - The EMBO journal, 1992 - embopress.org
When yeast cells are grown under conditions of amino acid limitation, transcription of amino
acid biosynthetic genes is increased through the action of the GCN4 transcriptional …

Translation of the Yeast Transcriptional Activator GCN4 Is Stimulated by Purine Limitation: Implications for Activation of the Protein Kinase GCN2

RJ Rolfes, AG Hinnebusch - Molecular and cellular biology, 1993 - Taylor & Francis
The transcriptional activator protein GCN4 is responsible for increased transcription of more
than 30 different amino acid biosynthetic genes in response to starvation for a single amino …

Genetic evidence for the interaction of the yeast transcriptional co-activator proteins GCN5 and ADA2

T Georgakopoulos, N Gounalaki, G Thireos - Molecular and General …, 1995 - Springer
The GCN5 and ADA2 proteins are required for the activation function of a number of
transcriptional activators in the yeast Saccharomyces cerevisiae. By using appropriate LexA …

Cooperative Regulation of ADE3 Transcription by Gcn4p and Bas1p in Saccharomyces cerevisiae

YJ Joo, JA Kim, JH Baek, KM Seong, KD Han… - Eukaryotic …, 2009 - Am Soc Microbiol
The one-carbon response regulon is essential for the biosynthesis of nucleic acids as well
as several amino acids. The ADE3 gene is known to encode a crucial one-carbon regulon …

Yeast upstream activator protein GCN4 can stimulate transcription when its binding site replaces the TATA element.

W Chen, K Struhl - The EMBO Journal, 1989 - embopress.org
We replaced the required TATA element of a yeast gal‐his3 promoter by a binding site for
GCN4, a protein that normally activates transcription when bound upstream of a TATA …

GCN4, a eukaryotic transcriptional activator protein, binds as a dimer to target DNA.

IA Hope, K Struhl - The EMBO journal, 1987 - embopress.org
The eukaryotic transcriptional activator protein, GCN4, synthesized in vitro from the cloned
gene, binds specifically to the promoters of yeast amino acid biosynthetic genes. Previous …

Regulation of GCN4 Expression in Yeast: Gene-Specific Translational Control by Phosphorylation of eIF-2α

AG Hinnebusch, RC Wek, TE Dever, AM Cigan… - … Regulation of Gene …, 1993 - Springer
The GCN4 protein of Saccharomyces cerevisiae is a positive regulator of more than 30
unlinked genes encoding enzymes in 11 different amino acid biosynthetic pathways. GCN4 …

Mutations that define the optimal half-site for binding yeast GCN4 activator protein and identify an ATF/CREB-like repressor that recognizes similar DNA sites

JW Sellers, AC Vincent, K Struhl - Molecular and cellular biology, 1990 - Am Soc Microbiol
The yeast GCN4 transcriptional activator protein binds as a dimer to a dyad-symmetric
sequence, indicative of a protein-DNA complex in which two protein monomers interact with …