Comparative transcriptome analysis reveals key epigenetic targets in SARS-CoV-2 infection

M Salgado-Albarrán, EI Navarro-Delgado… - NPJ systems biology …, 2021 - nature.com
COVID-19 is an infection caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome
coronavirus 2), which has caused a global outbreak. Current research efforts are focused on …

Comparative transcriptome analysis reveals the intensive early stage responses of host cells to SARS-CoV-2 infection

J Sun, F Ye, A Wu, R Yang, M Pan, J Sheng… - Frontiers in …, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a widespread
outbreak of highly pathogenic coronavirus disease 2019 (COVID-19). It is therefore …

A path-based analysis of infected cell line and COVID-19 patient transcriptome reveals novel potential targets and drugs against SARS-CoV-2

P Agrawal, N Sambaturu, G Olgun… - Frontiers in …, 2022 - frontiersin.org
Most transcriptomic studies of SARS-CoV-2 infection have focused on differentially
expressed genes, which do not necessarily reveal the genes mediating the transcriptomic …

Transcriptional and epi-transcriptional dynamics of SARS-CoV-2 during cellular infection

JJY Chang, D Rawlinson, ME Pitt, G Taiaroa… - Cell Reports, 2021 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses subgenomic RNA
(sgRNA) to produce viral proteins for replication and immune evasion. We apply long-read …

The transcriptomic profiling of SARS-CoV-2 compared to SARS, MERS, EBOV, and H1N1

AM Alsamman, H Zayed - PloS one, 2020 - journals.plos.org
The SARS-CoV-2 (COVID-19) pandemic is a global crisis that threatens our way of life. As of
November 18, 2020, SARS-CoV-2 has claimed more than 1,342,709 lives, with a global …

Gene expression profiling of SARS-CoV-2 infections reveal distinct primary lung cell and systemic immune infection responses that identify pathways relevant in …

MA Moni, JMW Quinn, N Sinmaz… - Briefings in …, 2021 - academic.oup.com
To identify key gene expression pathways altered with infection of the novel coronavirus
SARS-CoV-2, we performed the largest comparative genomic and transcriptomic analysis to …

[HTML][HTML] Transcriptomics secondary analysis of severe human infection with SARS-CoV-2 identifies gene expression changes and predicts three transcriptional …

J Clancy, CS Hoffmann, BE Pickett - Computational and Structural …, 2023 - Elsevier
SARS-CoV-2 is the causative agent of COVID-19, which has greatly affected human health
since it first emerged. Defining the human factors and biomarkers that differentiate severe …

Transcriptomic signature differences between SARS-CoV-2 and influenza virus infected patients

S Bibert, N Guex, J Lourenco, T Brahier… - Frontiers in …, 2021 - frontiersin.org
The reason why most individuals with COVID-19 have relatively limited symptoms while
other develop respiratory distress with life-threatening complications remains unknown …

SARS-CoV-2 infection initiates interleukin-17-enriched transcriptional response in different cells from multiple organs

MZ Hasan, S Islam, K Matsumoto, T Kawai - Scientific reports, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has emerged as a
pandemic. Paucity of information concerning the virus and therapeutic interventions have …

Bulk and single-cell gene expression profiling of SARS-CoV-2 infected human cell lines identifies molecular targets for therapeutic intervention

W Emanuel, M Kirstin, F Vedran, D Asija, GL Theresa… - BioRxiv, 2020 - biorxiv.org
Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is an ongoing global health threat …