W Shao, D Peng, X Wang - Journal of Clinical Neuroscience, 2017 - Elsevier
Alzheimer's disease (AD) is the most common type of dementia and has caused a major global health concern. Understanding the etiology of AD can be beneficial for the diagnosis …
C Van Cauwenberghe, C Van Broeckhoven… - Genetics in …, 2016 - nature.com
The search for the genetic factors contributing to Alzheimer disease (AD) has evolved tremendously throughout the years. It started from the discovery of fully penetrant mutations …
C Medway, K Morgan - Neuropathology and applied …, 2014 - Wiley Online Library
For two decades the search for genes involved in A lzheimer's disease brought little reward; it was not until the advent of genome‐wide association studies (GWAS) that genetic …
N Brouwers, K Sleegers, C Van Broeckhoven - Annals of medicine, 2008 - Taylor & Francis
Alzheimer's disease (AD) is a complex disorder of the central nervous system (CNS). Molecular genetic research has provided a wealth of information regarding the genetic …
AC Naj, GD Schellenberg… - American Journal of …, 2017 - Wiley Online Library
Alzheimer's disease (AD)(MIM: 104300) is a highly heritable disease with great complexity in its genetic contributors, and represents the most common form of dementia. With the …
C Bellenguez, B Grenier-Boley, JC Lambert - Current opinion in …, 2020 - Elsevier
Highlights•More than 40 loci of interest have been associated with the risk of developing AD.•Recent genetic data clearly implicate microglia as involved in the pathophysiological …
E Bagyinszky, YC Youn, SSA An… - Clinical interventions in …, 2014 - Taylor & Francis
Alzheimer's disease (AD) is a complex and heterogeneous neurodegenerative disorder, classified as either early onset (under 65 years of age), or late onset (over 65 years of age) …
S Carmona, J Hardy, R Guerreiro - Handbook of clinical neurology, 2018 - Elsevier
Alzheimer disease (AD), a progressive and neurodegenerative disease, is the most common form of dementia with high incidence in elderly people. Neuropathologically the disease is …
N Ertekin-Taner - Alzheimer's research & therapy, 2010 - Springer
Since the 1990s, the genetics of Alzheimer disease (AD) has been an active area of research. The identification of deterministic mutations in the APP, PSEN1, and PSEN2 …