Network-based approaches are powerful and beneficial tools to study complex systems in
their entirety, elucidating the essential factors that turn the multitude of individual elements …

Life-time experiences are thought to influence the risk to develop the neurodegenerative
disorder Alzheimer's disease (AD). In particular, early-life stress (ES) may modulate the …

Studies of gene expression in Alzheimer's disease (AD) have revealed tissue-level and cell-
type specific changes, highlighting the importance of regional heterogeneity in the disease's …

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder that is influenced by
genetic and environmental risk factors, such as inheritance of ε4 allele of APOE (APOE4) …

Background Alzheimer's disease (AD) is a devastating neurodegenerative disorder affecting
44 million people worldwide, leading to cognitive decline, memory loss, and significant …

Alzheimer's Disease (AD) is a complex neurodegenerative disease that gravely affects
patients and imposes an immense burden on caregivers. Apolipoprotein E4 (APOE4) has …

Background: Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the
most common cause of dementia in the United States. In spite of evidence of females having …

Alzheimer's disease (AD) progresses with memory loss and neuropsychiatric symptoms
associated with cell specific vulnerability in memory-and emotion-related neural circuits …

Background: Defining cellular mechanisms that drive Alzheimer's disease (AD)
pathogenesis and progression will be aided by studies defining how gene expression …

Mouse models of human diseases are invaluable tools for studying pathogenic mechanisms
and testing interventions and therapeutics. For disorders such as Alzheimer's disease in …