Background Elevated systematic inflammation is a hallmark of aging, but the association of
long-term inflammation trajectories with subsequent aging phenotypes has been little …

Background. Associations of inflammation with age-related pathologies are documented;
however, it is not understood how changes in inflammation over time impact healthy aging …

Background: The importance of chronic inflammation as a determinant of aging phenotypes
may have been underestimated in previous studies that used a single measurement of …

OBJECTIVES: To evaluate whether high levels of C‐reactive protein (CRP) in serum are
associated with greater risk of all‐cause dementia or mortality in the oldest‐old. DESIGN …

BACKGROUND: Raised levels of C-reactive protein (CRP), a marker of low grade systemic
inflammation, is common in ageing populations although the relevance of very highly …

Background Evidence suggests that systemic inflammation may have a mechanistic role in
age-related frailty, yet prospective data is limited. We examined whether systemic …

Objective The aim of this exploratory study was to investigate the development of low‐grade
inflammation during ageing and its relationship with frailty. Methods The trajectories of 18 …

Objectives Aims of the study were 1) to investigate the association of C-reactive protein
(CRP) with lipid (ie total, LDL, and HDL cholesterol, triglycerides) concentrations, and to …

BACKGROUND: C-reactive protein (CRP) is a nonspecific marker of inflammation that is
increased in the brain and serum of patients with Alzheimer's disease (AD), and has been …

Subjective age, or how young or old individuals experience themselves to be, is related to a
range of health-related outcomes in old age, including mortality risk. Little is known …