Cognitive impact of COVID-19: looking beyond the short term

S Miners, PG Kehoe, S Love - Alzheimer's research & therapy, 2020 - Springer
COVID-19 is primarily a respiratory disease but up to two thirds of hospitalised patients show
evidence of central nervous system (CNS) damage, predominantly ischaemic, in some …

SARS-CoV-2 infection of microglia elicits proinflammatory activation and apoptotic cell death

GU Jeong, J Lyu, KD Kim, YC Chung… - Microbiology …, 2022 - Am Soc Microbiol
Accumulating evidence suggests that severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection causes various neurological symptoms in patients with coronavirus …

Infection of brain pericytes underlying neuropathology of COVID-19 patients

M Bocci, C Oudenaarden, X Sàenz-Sardà… - International journal of …, 2021 - mdpi.com
A wide range of neurological manifestations have been associated with the development of
COVID-19 following SARS-CoV-2 infection. However, the etiology of the neurological …

Proteomic and transcriptomic profiling of brainstem, cerebellum and olfactory tissues in early-and late-phase COVID-19

J Radke, J Meinhardt, T Aschman, RL Chua… - Nature …, 2024 - nature.com
Neurological symptoms, including cognitive impairment and fatigue, can occur in both the
acute infection phase of coronavirus disease 2019 (COVID-19) and at later stages, yet the …

Amyloid processing in COVID‐19‐associated neurological syndromes

OJ Ziff, NJ Ashton, PR Mehta, R Brown… - Journal of …, 2022 - Wiley Online Library
SARS‐CoV‐2 infection can damage the nervous system with multiple neurological
manifestations described. However, there is limited understanding of the mechanisms …

Hippocampal subfield abnormalities and biomarkers of pathologic brain changes: from SARS-CoV-2 acute infection to post-COVID syndrome

M Díez-Cirarda, M Yus-Fuertes, R Sanchez-Sanchez… - …, 2023 - thelancet.com
Background Cognitive deficits are among the main disabling symptoms in COVID-19
patients and post-COVID syndrome (PCS). Within brain regions, the hippocampus, a key …

Neurological complications associated with the blood-brain barrier damage induced by the inflammatory response during SARS-CoV-2 infection

I Alquisiras-Burgos, I Peralta-Arrieta… - Molecular …, 2021 - Springer
The main discussion above of the novel pathogenic severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection has focused substantially on the immediate risks and …

[HTML][HTML] The effects of the COVID-19 pandemic on people with dementia

K Numbers, H Brodaty - Nature Reviews Neurology, 2021 - nature.com
The COVID-19 pandemic has posed unique risks to people with Alzheimer disease and
dementia. Research from 2020 has shown that these people have a relatively high risk of …

Vascular mechanisms leading to progression of mild cognitive impairment to dementia after COVID-19: Protocol and methodology of a prospective longitudinal …

CD Owens, C Bonin Pinto, P Mukli, Z Szarvas… - PLoS …, 2023 - journals.plos.org
Introduction Mild cognitive impairment (MCI) is a prodromal stage to dementia, affecting up
to 20% of the aging population worldwide. Patients with MCI have an annual conversion rate …

Potential novel role of COVID-19 in Alzheimer's disease and preventative mitigation strategies

SX Naughton, U Raval… - Journal of Alzheimer's …, 2020 - content.iospress.com
There are a number of potential implications for the field of Alzheimer's disease (AD)
stemming from the global spread of SARS-CoV-2. Neuroinflammation is known to be a …