Background. Individual measurements of inflammation have been utilized to assess adverse
outcomes risk in older adults with varying degrees of success. This study was designed to …

OBJECTIVES: Several peripheral blood markers of inflammation have demonstrated
prognostic ability, but the value of combining multiple markers as a measure of inflammatory …

OBJECTIVES: To investigate whether interleukin‐6 (IL‐6), C‐reactive protein (CRP) and
tumor necrosis factor‐alpha (TNF‐α) protein levels predict all‐cause mortality in older …

Background. Associations of inflammation with age-related pathologies are documented;
however, it is not understood how changes in inflammation over time impact healthy aging …

Background: The importance of chronic inflammation as a determinant of aging phenotypes
may have been underestimated in previous studies that used a single measurement of …

PURPOSE: To review findings from major epidemiologic studies regarding risk factors for
and consequences of elevated markers of inflammation in older adults. RESULTS: Most …

Background. Inflammation plays a major role in both aging and chronic disease.
Longitudinal studies in very old people can improve our understanding of these processes …

In the past decade inflammatory markers have emerged as strong independent risk
indicators for cardiovascular disease. Even though adults over the age of 65 experience a …

Background Aging is one factor believed to contribute to processes that underlie chronic low-
grade inflammation in older adults. Moreover, more recent studies have suggested that …

Ageing is associated with low-grade inflammation and markers such as IL-6 possess
prognostic value. Tumour necrosis-alpha (TNF-α) initiates the inflammatory cascade and …