The novel coronavirus severe acute respiratory syndrome coronavirus 2 causing the
Coronavirus disease (COVID-19) pandemic has ravaged the world with over 72 million total …

Within the past several decades, the emergence of new viral diseases with severe health
complications and mortality is evidence of an age-dependent, compromised bodily response …

The ongoing pandemic severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
causes a disproportionate number of severe cases and deaths in older adults. Severe SARS …

Morbidity and mortality in response to SARS-CoV-2 infection are significantly elevated in
people of advanced age. To understand the underlying biology of this phenotype, we utilize …

The public health consequences of the epidemic of severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) infections may well go beyond the current burden on hospital …

The immune system of patients infected by SARS-CoV-2 is severely impaired. Detailed
investigation of T cells and cytokine production in patients affected by COVID-19 pneumonia …

Older individuals are at higher risk of SARS-CoV-2 infection and severe outcomes, but the
underlying mechanisms are incompletely understood. In addition, how age modulates SARS …

Background The coronavirus disease 2019 (COVID-19) pandemic continues to produce
substantial morbidity and mortality. To understand the reasons for the wide-spectrum …

The destructive effects of coronavirus disease 2019 (COVID-19) on the elderly and people
with cardiovascular disease have been proven. New findings shed light on the role of aging …

Bearing a strong resemblance to the phenotypic and functional remodeling of the immune
system that occurs during aging (termed immunesenescence), the immune response to …