Natural products in drug discovery–creating a new vision

GA Cordell - Phytochemistry Reviews, 2002 - Springer
Abstract “If only they had chosen to develop natural product drugs in a sustainable manner
at the turn of the century”. In 2050, when the Earth has a population of at least 9 billion, will …

The impact of natural products upon modern drug discovery

A Ganesan - Current opinion in chemical biology, 2008 - Elsevier
In the period 1970–2006, a total of 24 unique natural products were discovered that led to
an approved drug. We analyze these successful leads in terms of drug-like properties, and …

Natural products in the process of finding new drug candidates

P Vuorela, M Leinonen, P Saikku… - Current medicinal …, 2004 - ingentaconnect.com
Natural derived or originated compounds still play a major role as drugs, and as lead
structures for the development of synthetic molecules. About 50% of the drugs introduced to …

Drug discovery from medicinal plants

MJ Balunas, AD Kinghorn - Life sciences, 2005 - Elsevier
Current research in drug discovery from medicinal plants involves a multifaceted approach
combining botanical, phytochemical, biological, and molecular techniques. Medicinal plant …

Therapeutic applications of natural products in herbal medicines, biodiscovery programs, and biomedicine

P Wangchuk - Journal of Biologically Active Products from Nature, 2018 - Taylor & Francis
Natural products had been one of the important sources of remedial agents for thousands of
years. From the data presented in this review, the utilization of biologically active natural …

Cheminformatics in natural product‐based drug discovery

Y Chen, J Kirchmair - Molecular Informatics, 2020 - Wiley Online Library
This review seeks to provide a timely survey of the scope and limitations of cheminformatics
methods in natural product‐based drug discovery. Following an overview of data resources …

[PDF][PDF] Plants in traditional medicinal system-future source of new drugs

SP Rout, KA Choudary, DM Kar, L Das… - Int J Pharm Pharm …, 2009 - researchgate.net
The approach to new drugs through natural products has proved to be the single most
successful strategy for the discovery of new drugs, but in recent years its use has been …

[HTML][HTML] Discovery and resupply of pharmacologically active plant-derived natural products: A review

AG Atanasov, B Waltenberger… - Biotechnology …, 2015 - Elsevier
Medicinal plants have historically proven their value as a source of molecules with
therapeutic potential, and nowadays still represent an important pool for the identification of …

New perspectives on how to discover drugs from herbal medicines: CAM′ S outstanding contribution to modern therapeutics

SY Pan, SF Zhou, SH Gao, ZL Yu… - Evidence‐Based …, 2013 - Wiley Online Library
With tens of thousands of plant species on earth, we are endowed with an enormous wealth
of medicinal remedies from Mother Nature. Natural products and their derivatives represent …

[图书][B] Phytochemicals as lead compounds for new drug discovery

C Egbuna, S Kumar, JC Ifemeje, SM Ezzat… - 2019 - books.google.com
Phytochemicals as Lead Compounds for New Drug Discovery presents complete coverage
of the recent advances in the discovery of phytochemicals from medicinal plants as models …