[PDF][PDF] Molecular mechanisms of chemoresistance in oral cancer

C Wang, XQ Liu, JS Hou, JN Wang, HZ Huang - Chin J Dent Res, 2016 - cjdr.cndent.com
Oral cancer is an aggressive disease with the propensity for local recurrence and distal
metastasis in the head and neck region. Currently, cisplatin-based chemotherapy or …

Tumour microenvironment and aberrant signaling pathways in cisplatin resistance and strategies to overcome in oral cancer

S Biswal, M Panda, RK Sahoo, SK Tripathi… - Archives of Oral …, 2023 - Elsevier
Objective Oral cancer is the sixteenth most prevalent cancer in the world and the third-most
in India. Despite of several treatment modalities, the cure rate of oral cancer is still low due to …

[HTML][HTML] Major molecular signaling pathways in oral cancer associated with therapeutic resistance

S Usman, A Jamal, MT Teh, A Waseem - Frontiers in Oral Health, 2021 - frontiersin.org
Oral cancer is a sub-category of head and neck cancers that primarily initiates in the oral
cavity. The primary treatment option for oral cancer remains surgery but it is associated with …

[HTML][HTML] The molecular basis and therapeutic aspects of cisplatin resistance in oral squamous cell carcinoma

Y Cheng, S Li, L Gao, K Zhi, W Ren - Frontiers in oncology, 2021 - frontiersin.org
Oral squamous cell carcinoma (OSCC) is a kind of malignant tumors with low survival rate
and prone to have early metastasis and recurrence. Cisplatin is an alkylating agent which …

[HTML][HTML] Molecular mechanisms of chemotherapy resistance in head and neck cancers

Y Kanno, CY Chen, HL Lee, JF Chiou… - Frontiers in …, 2021 - frontiersin.org
Chemotherapy resistance is a huge barrier for head and neck cancer (HNC) patients and
therefore requires close attention to understand its underlay mechanisms for effective …

The role of non‐coding RNAs in drug resistance of oral squamous cell carcinoma and therapeutic potential

X Meng, QY Lou, WY Yang, YR Wang… - Cancer …, 2021 - Wiley Online Library
Oral squamous cell carcinoma (OSCC), the eighth most prevalent cancer in the world, arises
from the interaction of multiple factors including tobacco, alcohol consumption, and betel …

Genetic alterations and clinical dimensions of oral cancer: a review

K Karunakaran, R Muniyan - Molecular Biology Reports, 2020 - Springer
Oral cancer ranks sixth most prevalent type of cancer worldwide due to its alarming increase
every year. Progression of oral cancer depends on various heterogeneity pathways, but their …

ROS enhances the cytotoxicity of cisplatin by inducing apoptosis and autophagy in tongue squamous cell carcinoma cells

DF Xue, ST Pan, G Huang, JX Qiu - … journal of biochemistry & cell biology, 2020 - Elsevier
Cisplatin is one of the most widely used anticancer agents for patients with tongue
squamous cell carcinoma (TSCC), but its efficacy is limited by chemoresistance …

[HTML][HTML] Upregulation of MDR-and EMT-related molecules in cisplatin-resistant human oral squamous cell carcinoma cell lines

HS Choi, YK Kim, PY Yun - International Journal of Molecular Sciences, 2019 - mdpi.com
Cisplatin is one of the major drugs used in oral cancer treatments, but its usage can be
limited by acquired drug resistance. In this study, we established three cisplatin-resistant …

[HTML][HTML] MicroRNAs as the pivotal regulators of cisplatin resistance in head and neck cancers

F Tolue Ghasaban, A Maharati, AS Zangouei… - Cancer cell …, 2023 - Springer
Although, there is a high rate of good prognosis in early stage head and neck tumors, about
half of these tumors are detected in advanced stages with poor prognosis. A combination of …