Organismal aging is driven by interconnected molecular changes encompassing internal
and extracellular factors. Combinational analysis of high-throughput 'multi-omics' datasets …

Aging is a complex process that accompanied by molecular and cellular alterations. The
identification of tissue-/cell type-specific biomarkers of aging and elucidation of the detailed …

Age is the key risk factor for diseases and disabilities of the elderly. Efforts to tackle age-
related diseases and increase healthspan have suggested targeting the ageing process …

Recent technological advances that allow faster and cheaper DNA sequencing are now
driving biological and medical research. In this review, we provide an overview of state-of …

Aging is closely related to the occurrence of human diseases; however, its exact biological
mechanism is unclear. Advancements in high-throughput technology provide new …

The identification of plasma proteins that systematically change with age and, independent
of chronological age, predict accelerated decline of health is an expanding area of research …

Organismal ageing results from interlinked molecular changes in multiple organs over time.
The study of ageing at the molecular level is complicated by varying decay characteristics …

Age is the strongest risk factor for many diseases including neurodegenerative disorders,
coronary heart disease, type 2 diabetes and cancer. Due to increasing life expectancy and …

Motivation: Numerous microarray studies of aging have been conducted, yet given the noisy
nature of gene expression changes with age, elucidating the transcriptional features of …

Normal ageing is associated with diverse physiological changes in all organ systems but the
rate and extent of these changes vary markedly among individuals. One aspect of ageing …