Aging is characterized by a progressive loss of physiological integrity, leading to impaired
function and increased vulnerability to death. This deterioration is the primary risk factor for …

Background Identifying biological pathways that vary across the age spectrum can provide
insight into fundamental mechanisms that impact disease and frailty in the elderly. Few …

Aging is a fundamental biological process accompanied by a general decline in tissue
function. Indeed, as the lifespan increases, age-related dysfunction, such as cognitive …

Aging is a predominant risk factor for several chronic diseases that limit healthspan.
Mechanisms of aging are thus increasingly recognized as potential therapeutic targets …

Multi-omics approach nowadays increasingly applied to molecular research in many fields
of life sciences. Biogerontology is not an exception; multi-omics gives possibility to evaluate …

Aging is a complex process that results in compromised biological functions of the organism
and increased susceptibility to disease and death. Although the molecular basis of aging is …

The molecular changes that occur with aging are not well understood,,–. Here, we
performed longitudinal and deep multiomics profiling of 106 healthy individuals from 29 to …

Recent statistics indicate that the human population is ageing rapidly. Healthy, but also
diseased, elderly people are increasing. This trend is particularly evident in Western …

Aging is an inevitable outcome of life, characterized by progressive decline in tissue and
organ function and increased risk of mortality. Accumulating evidence links aging to genetic …

Age-related conditions are the leading causes of death and health-care costs. Reducing the
rate of aging would have enormous medical and financial benefits. Myriad genes and …