[HTML][HTML] Long-term neural embedding of childhood adversity in a population-representative birth cohort followed for 5 decades

MZ Gehred, AR Knodt, A Ambler, KJ Bourassa… - Biological …, 2021 - Elsevier
Background Childhood adversity has been previously associated with alterations in brain
structure, but heterogeneous designs, methods, and measures have contributed to mixed …

Latent Profiles of Childhood Adversity, Adolescent Mental Health, and Neural Network Connectivity

FA Hardi, AM Beltz, V McLoyd… - JAMA Network …, 2024 - jamanetwork.com
Importance Adverse childhood experiences are pervasive and heterogeneous, with
potential lifelong consequences for psychiatric morbidity and brain health. Existing research …

Enhanced prefrontal-amygdala connectivity following childhood adversity as a protective mechanism against internalizing in adolescence

RJ Herringa, CA Burghy, DE Stodola, ME Fox… - Biological Psychiatry …, 2016 - Elsevier
Background Much research has focused on the deleterious neurobiological effects of
childhood adversity that may underlie internalizing disorders. Although most youth show …

[HTML][HTML] Characterizing the impact of adversity, abuse, and neglect on adolescent amygdala resting-state functional connectivity

TW Cheng, KL Mills, OM Dominguez… - Developmental cognitive …, 2021 - Elsevier
Characterizing typologies of childhood adversity may inform the development of risk profiles
and corresponding interventions aimed at mitigating its lifelong consequences. A …

Rethinking concepts and categories for understanding the neurodevelopmental effects of childhood adversity

KE Smith, SD Pollak - Perspectives on psychological science, 2021 - journals.sagepub.com
Discovering the processes through which early adverse experiences affect children's
nervous-system development, health, and behavior is critically important for developing …

Network structure reveals clusters of associations between childhood adversities and development outcomes

MA Sheridan, F Shi, AB Miller, C Salhi… - Developmental …, 2020 - Wiley Online Library
Exposure to childhood adversity is common and associated with a host of negative
developmental outcomes. The most common approach used to examine the consequences …

Testing deprivation and threat: A preregistered network analysis of the dimensions of early adversity

S Carozza, J Holmes, DE Astle - Psychological Science, 2022 - journals.sagepub.com
Despite abundant evidence of the detrimental effects of childhood adversity, its nature and
underlying mechanisms remain contested. One influential theory, the dimensional model of …

Association of prenatal exposure to early-life adversity with neonatal brain volumes at birth

RL Triplett, RE Lean, A Parikh, JP Miller… - JAMA network …, 2022 - jamanetwork.com
Importance Exposure to early-life adversity alters the structural development of key brain
regions underlying neurodevelopmental impairments. The association between prenatal …

[HTML][HTML] General and specific effects of early-life psychosocial adversities on adolescent grey matter volume

ND Walsh, T Dalgleish, MV Lombardo, VJ Dunn… - NeuroImage: Clinical, 2014 - Elsevier
Exposure to childhood adversities (CA) is associated with subsequent alterations in regional
brain grey matter volume (GMV). Prior studies have focused mainly on severe neglect and …

Childhood adversity and neural development: A systematic review

KA McLaughlin, D Weissman… - Annual review of …, 2019 - annualreviews.org
An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …