Background. Associations of inflammation with age-related pathologies are documented;
however, it is not understood how changes in inflammation over time impact healthy aging …

Background: The importance of chronic inflammation as a determinant of aging phenotypes
may have been underestimated in previous studies that used a single measurement of …

Background Evidence suggests that systemic inflammation may have a mechanistic role in
age-related frailty, yet prospective data is limited. We examined whether systemic …

Background Elevated systematic inflammation is a hallmark of aging, but the association of
long-term inflammation trajectories with subsequent aging phenotypes has been little …

OBJECTIVES: To describe changes in interleukin‐6 (IL‐6) and C‐reactive protein (CRP)
and to determine how changes are related to mortality in elderly people. DESIGN …

Background In the elderly, chronic low-grade inflammation (inflammaging) is a risk factor for
the development of aging-related diseases and frailty. Using data from several thousand …

OBJECTIVES: To investigate whether higher circulating levels of C‐reactive protein (CRP),
interleukin‐6 (IL‐6), and α1‐antichymotrypsin (ACT) are associated with worse cognitive …

Background. Individual measurements of inflammation have been utilized to assess adverse
outcomes risk in older adults with varying degrees of success. This study was designed to …

In the past decade inflammatory markers have emerged as strong independent risk
indicators for cardiovascular disease. Even though adults over the age of 65 experience a …

Objectives To investigate long‐term variability in serum high‐sensitivity C‐reactive protein
(CRP) and interleukin‐6 (IL‐6) and to determine associated risk factors for high‐risk …