Predicting cellular position in the Drosophila embryo from Single-Cell Transcriptomics data

J Tanevski, T Nguyen, B Truong, N Karaiskos… - bioRxiv, 2019 - biorxiv.org
Single-cell RNA-seq technologies are rapidly evolving but while very informative, in
standard scRNAseq experiments the spatial organization of the cells in the tissue of origin is …

Gene selection for optimal prediction of cell position in tissues from single-cell transcriptomics data

J Tanevski, T Nguyen, B Truong… - Life Science …, 2020 - life-science-alliance.org
Single-cell RNA-sequencing (scRNAseq) technologies are rapidly evolving. Although very
informative, in standard scRNAseq experiments, the spatial organization of the cells in the …

[HTML][HTML] Prediction of gene expression in embryonic structures of Drosophila melanogaster

AA Samsonova, M Niranjan, S Russell… - PLoS computational …, 2007 - journals.plos.org
Understanding how sets of genes are coordinately regulated in space and time to generate
the diversity of cell types that characterise complex metazoans is a major challenge in …

The winning methods for predicting cellular position in the DREAM single-cell transcriptomics challenge

VVH Pham, X Li, B Truong, T Nguyen… - Briefings in …, 2021 - academic.oup.com
Motivation Predicting cell locations is important since with the understanding of cell
locations, we may estimate the function of cells and their integration with the spatial …

Methods and tools for spatial mapping of single-cell RNAseq clusters in Drosophila

SE Mohr, SG Tattikota, J Xu, J Zirin, Y Hu, N Perrimon - Genetics, 2021 - academic.oup.com
Single-cell RNA sequencing (scRNAseq) experiments provide a powerful means to identify
clusters of cells that share common gene expression signatures. A major challenge in …

[HTML][HTML] Feature Selection for Topological Proximity Prediction of Single-Cell Transcriptomic Profiles in Drosophila Embryo Using Genetic Algorithm

S Gupta, AK Verma, S Ahmad - Genes, 2020 - mdpi.com
Single-cell transcriptomics data, when combined with in situ hybridization patterns of specific
genes, can help in recovering the spatial information lost during cell isolation. Dialogue for …

MLSpatial: A machine-learning method to reconstruct the spatial distribution of cells from scRNA-seq by extracting spatial features

M Zhu, C Li, K Lv, H Guo, R Hou, G Tian… - Computers in Biology and …, 2023 - Elsevier
Motivation Single-cell RNA sequencing (scRNA-seq) technologies allow us to interrogate
the state of an individual cell within its microenvironment. However, prior to sequencing …

Mapping lineage-resolved scRNA-seq data with spatial transcriptomics using TemSOMap

X Pan, A Danies-Lopez, X Zhang - bioRxiv, 2024 - biorxiv.org
Spatial transcriptomics (ST) has become a powerful technique that advances the study of
cell spatial organization and cell-cell interactions. While ST can preserve location …

[HTML][HTML] Model-based prediction of spatial gene expression via generative linear mapping

Y Okochi, S Sakaguchi, K Nakae, T Kondo… - Nature …, 2021 - nature.com
Decoding spatial transcriptomes from single-cell RNA sequencing (scRNA-seq) data has
become a fundamental technique for understanding multicellular systems; however, existing …

High-resolution spatiotemporal transcriptomic maps of developing Drosophila embryos and larvae

M Wang, Q Hu, T Lv, Y Wang, Q Lan, Z Tu, R Xiang… - bioRxiv, 2021 - biorxiv.org
Drosophila has long been a successful model organism in multiple fields such as genetics
and developmental biology. Drosophila genome is relatively smaller and less redundant, yet …