Monozygotic twins: Identical or distinguishable for science and law?

S Turrina, E Bortoletto, G Giannini… - Medicine, Science and …, 2021 - journals.sagepub.com
Monozygotic twins, also known as monovular twins, share an identical genetic heritage
because they are two individuals who derive from the same zygote. For this reason, they …

[HTML][HTML] Finding the needle in the haystack: differentiating “identical” twins in paternity testing and forensics by ultra-deep next generation sequencing

J Weber-Lehmann, E Schilling, G Gradl… - Forensic Science …, 2014 - Elsevier
Monozygotic (MZ) twins are considered being genetically identical, therefore they cannot be
differentiated using standard forensic DNA testing. Here we describe how identification of …

Editors' pick: Molecular genetic investigative leads to differentiate monozygotic twins

B Budowle - Investigative Genetics, 2014 - Springer
Monozygotic twins arise from a single fertilized egg and, thus, for practical purposes are
genetically identical. Therefore, in cases where one of the identical twins is associated with …

Technical strategy for monozygotic twin discrimination by single-nucleotide variants

W Sun, Z Wang, S Wen, A Huang, H Li, L Jiang… - International Journal of …, 2024 - Springer
Monozygotic (MZ) twins are theoretically genetically identical. Although they are revealed to
accumulate mutations after the zygote splits, discriminating between twin genomes remains …

Identification of the perpetrator among identical twins using next-generation sequencing technology: A case report

L Yuan, X Chen, Z Liu, Q Liu, A Song, G Bao… - Forensic Science …, 2020 - Elsevier
Background Monozygotic (MZ) twins, considered genetically identical, cannot be
distinguished using regular short tandem repeats (STR) typing, thus presenting a challenge …

The germlines of male monozygotic (MZ) twins: Very similar, but not identical

B Rolf, M Krawczak - Forensic Science International: Genetics, 2021 - Elsevier
In 2012, a thought experiment in this journal suggested that paternity cases involving
monozygotic (MZ) twins as putative fathers could be solved by means of whole genome …

Research progress on discrimination of monozygotic twins

XU Qian-Nan, LI Cheng-Tao, LIU Xi-Ling - Journal of Forensic Medicine, 2018 - fyxzz.cn
Individual identification plays an import role in the practice of forensic medicine, and often
provides crucial evidence for the analysis and detection of criminal cases. However, for …

Discrimination of monozygotic twins using mtDNA heteroplasmy through probe capture enrichment and massively parallel sequencing

Y Zhong, K Zeng, A Adnan, YZ Li, X Hou, Y Pan… - International Journal of …, 2023 - Springer
Differentiating between monozygotic (MZ) twins remains difficult because they have the
same genetic makeup. Applying the traditional STR genotyping approach cannot …

How to distinguish genetically between an alleged father and his monozygotic twin: a thought experiment

M Krawczak, DN Cooper, F Fändrich, W Engel… - Forensic Science …, 2012 - Elsevier
Recently, a first direct estimate of the single base-pair substitution rate in the human
germline was derived from genome-wide DNA sequence data. This result has shed new …

Differentiating between monozygotic twins in forensics through next generation mtGenome sequencing

Z Wang, S Zhang, Y Bian, C Li - Forensic Science International: Genetics …, 2015 - Elsevier
Monozygotic (MZ) twins, considered being genetically identical, cannot be distinguished one
from another by forensic short tandem repeat (STR) profiling. The high mutation rate of the …