Epigenetic clock and methylation studies in elephants

NA Prado, JL Brown, JA Zoller, A Haghani, M Yao… - Aging cell, 2021 - Wiley Online Library
Age‐associated DNA‐methylation profiles have been used successfully to develop highly
accurate biomarkers of age (" epigenetic clocks") in humans, mice, dogs, and other species …

[HTML][HTML] Epigenetic clock and methylation studies in cats

K Raj, B Szladovits, A Haghani, JA Zoller, CZ Li… - GeroScience, 2021 - Springer
Human DNA methylation profiles have been used successfully to develop highly accurate
biomarkers of aging (“epigenetic clocks”). Although these human epigenetic clocks are not …

[HTML][HTML] Epigenetic clock and methylation studies in vervet monkeys

AJ Jasinska, A Haghani, JA Zoller, CZ Li, A Arneson… - GeroScience, 2022 - Springer
DNA methylation-based biomarkers of aging have been developed for many mammals but
not yet for the vervet monkey (Chlorocebus sabaeus), which is a valuable non-human …

DNA methylation clocks for dogs and humans

S Horvath, AT Lu, A Haghani… - Proceedings of the …, 2022 - National Acad Sciences
DNA methylation profiles have been used to develop biomarkers of aging known as
epigenetic clocks, which predict chronological age with remarkable accuracy and show …

[HTML][HTML] Epigenetic clock and methylation studies in the rhesus macaque

S Horvath, JA Zoller, A Haghani, AJ Jasinska, K Raj… - GeroScience, 2021 - Springer
Methylation levels at specific CpG positions in the genome have been used to develop
accurate estimators of chronological age in humans, mice, and other species. Although …

[HTML][HTML] DNA methylation clocks for clawed frogs reveal evolutionary conservation of epigenetic aging

JA Zoller, E Parasyraki, AT Lu, A Haghani, C Niehrs… - GeroScience, 2024 - Springer
To address how conserved DNA methylation-based epigenetic aging is in diverse branches
of the tree of life, we generated DNA methylation data from African clawed frogs (Xenopus …

[HTML][HTML] DNA methylation age analysis of rapamycin in common marmosets

S Horvath, JA Zoller, A Haghani, AT Lu, K Raj… - GeroScience, 2021 - Springer
Human DNA methylation data have previously been used to develop highly accurate
biomarkers of aging (“epigenetic clocks”). Subsequent studies demonstrate that similar …

[HTML][HTML] DNA methylation aging clocks: challenges and recommendations

CG Bell, R Lowe, PD Adams, AA Baccarelli, S Beck… - Genome biology, 2019 - Springer
Epigenetic clocks comprise a set of CpG sites whose DNA methylation levels measure
subject age. These clocks are acknowledged as a highly accurate molecular correlate of …

DNA methylation markers of age (ing) in non‐model animals

M Tangili, AJ Slettenhaar, J Sudyka… - Molecular …, 2023 - Wiley Online Library
Inferring the chronological and biological age of individuals is fundamental to population
ecology and our understanding of ageing itself, its evolution, and the biological processes …

[HTML][HTML] A multi-tissue full lifespan epigenetic clock for mice

MJ Thompson, K Chwiałkowska, L Rubbi… - Aging (Albany …, 2018 - ncbi.nlm.nih.gov
Human DNA-methylation data have been used to develop highly accurate biomarkers of
aging (" epigenetic clocks"). Recent studies demonstrate that similar epigenetic clocks for …