Immunosenescence exacerbates the COVID-19

C Napoli, I Tritto, G Mansueto, E Coscioni… - … of Gerontology and …, 2020 - ncbi.nlm.nih.gov
Aging and senescence are complex processes associated with increased frailty (Calimport,
Bentley, & Stewart, 2019). Overall, many pathogens are more aggressive and prevalent in …

COVID-19 through the lens of gerontology

DG Le Couteur, RM Anderson… - The Journals of …, 2020 - academic.oup.com
The case-fatality rate for COVID-19 increases dramatically with age from 3% to 5% between
65 and 74 years, 4% to 11% between 75 and 84 years, and 10% to 27% above 85 years …

Besides population age structure, health and other demographic factors can contribute to understanding the COVID-19 burden

MR Nepomuceno, E Acosta… - Proceedings of the …, 2020 - National Acad Sciences
An insightful paper by Dowd et al.(1) highlights the importance of demography for analyzing
coronavirus disease 2019 (COVID-19)–related mortality. The authors underscore the role of …

COVID-19 and quarantine, a catalyst for ageism

N Barth, J Guyot, SA Fraser, M Lagacé… - Frontiers in public …, 2021 - frontiersin.org
In February 2021, France had more than 76,000 deaths due to COVID-19 and older adults
were heavily affected. Most measures taken to reduce the impact of COVID-19 (quarantine …

[HTML][HTML] Age-related morbidity and mortality among patients with COVID-19

SJ Kang, SI Jung - Infection & chemotherapy, 2020 - ncbi.nlm.nih.gov
Abstract On March 11, 2020, the World Health Organization declared coronavirus disease
(COVID-19), caused by the novel coronavirus severe acute respiratory syndrome …

A geroscience perspective on COVID-19 mortality

DEL Promislow - The journals of gerontology: Series A, 2020 - academic.oup.com
A novel coronavirus, SARS-CoV-2, emerged in December 2019, leading within a few
months to a global pandemic. COVID-19, the disease caused by this highly contagious virus …

[HTML][HTML] Effects of COVID-19 pandemic on health and wellbeing of older people: a comprehensive review

R Lekamwasam, S Lekamwasam - Annals of geriatric medicine and …, 2020 - ncbi.nlm.nih.gov
The pandemic is unavoidable; in addition to increased morbidity and mortality, they
profoundly affect people and economies at every level. The negative effects of pandemics …

Geriatric population during the COVID-19 pandemic: problems, considerations, exigencies, and beyond

K Dhama, SK Patel, R Kumar, J Rana… - Frontiers in public …, 2020 - frontiersin.org
The coronavirus disease 2019 (COVID-19) pandemic wreaked havoc worldwide, with more
than 20 million confirmed cases and nearly 0. 75 million deaths as of 10th August 2020 …

[PDF][PDF] COVID-19 is a disease of older people

DG Le Couteur, RM Anderson… - J Gerontol A Biol Sci Med …, 2020 - ravikollimd.com
COVID-19 is primarily a disease of older people. In the United States, 31% of cases of
COVID-19 have occurred in people over the age of 65 years and 6% over the age of 85 …

SARS-CoV-2, COVID-19 and the aging immune system

JM Bartleson, D Radenkovic, AJ Covarrubias… - Nature aging, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is a global health threat with
particular risk for severe disease and death in older adults and in adults with age-related …