Age is a major risk factor for severe outcome of the 2019 coronavirus disease (COVID-19). In
this study, we followed the hypothesis that particularly patients with accelerated epigenetic …

Chronological age is a risk factor for SARS-CoV-2 infection and severe COVID-19. Previous
findings indicate that epigenetic age could be altered in viral infection. However, the …

Background Aging has been reported as a major risk factor for severe symptoms and higher
mortality rates in COVID-19 patients. Molecular hallmarks such as epigenetic alterations and …

The global impact of the SARS-CoV-2 pandemic has been unprecedented, posing a
significant public health challenge. Chronological age has been identified as a key …

Background: COVID-19 displays an increased mortality rate and higher risk of severe
symptoms with increasing age, which is thought to be a result of the compromised immunity …

The SARS-CoV-2 infection determines the COVID-19 syndrome characterized, in the worst
cases, by severe respiratory distress, pulmonary and cardiac fibrosis, inflammatory cytokine …

Observational data from China, the United States, France, and Italy suggest that
chronological age is an adverse COVID-19 outcome risk factor, with older patients having a …

Within the past several decades, the emergence and spread of infectious diseases with
pandemic potential have endangered human lives. Coronavirus disease 2019 (COVID-19) …

The host epigenetic landscape rapidly changes during SARS-CoV-2 infection, and evidence
suggest that severe COVID-19 is associated with durable scars to the epigenome …

Background COVID-19 has a wide spectrum of clinical manifestations and given its impact
on morbidity and mortality, there is an unmet medical need to discover endogenous cellular …