Disulfidptosis-related signature predicts prognosis and characterizes the immune microenvironment in hepatocellular carcinoma

J Tang, X Peng, D Xiao, S Liu, Y Tao, L Shu - Cancer Cell International, 2024 - Springer
Background Disulfidptosis is a type of programmed cell death caused by excessive cysteine-
induced disulfide bond denaturation leading to actin collapse. Liver cancer has a poor …

[HTML][HTML] Construction of a novel disulfidptosis-related signature for improving outcomes in hepatocellular carcinoma: Observational study

X Chen, Q Liang, Y Zhou - Medicine, 2023 - journals.lww.com
Disulfidptosis is a novel form of metabolic-related regulated cell death (RCD) that is caused
by disulfide stress caused by the accumulation of excess cystine in the cell. Targeting …

[HTML][HTML] Disulfidptosis-related genes of prognostic signature and immune infiltration features in hepatocellular carcinoma supported by bulk and single-cell RNA …

Y Wang, Z Yuan, Q Zhu, J Ma, Q Lu… - Journal of …, 2024 - ncbi.nlm.nih.gov
Background Disulfidptosis is a new type of cellular death triggered in response to disulfide
stress and is strongly linked to the progression of malignancies. Hepatocellular carcinoma …

Identifying disulfidptosis subtypes in hepatocellular carcinoma through machine learning and preliminary exploration of its connection with immunotherapy

G Chen, G Zhang, Y Zhu, A Wu, J Fang, Z Yin… - Cancer Cell …, 2024 - Springer
Background Hepatocellular carcinoma (HCC) is a highly prevalent and deadly cancer, with
limited treatment options for advanced-stage patients. Disulfidptosis is a recently identified …

Disulfidptosis-related signatures for prognostic and immunotherapy reactivity evaluation in hepatocellular carcinoma

J Zhao, Z Luo, R Fu, J Zhou, S Chen, J Wang… - European Journal of …, 2023 - Springer
Background Hepatocellular carcinoma (HCC) is one of the most common cancers in the
world and a nonnegligible health concern on a worldwide scale. Disulfidptosis is a novel …

Development of the RF-GSEA method for identifying disulfidptosis-related genes and application in hepatocellular carcinoma

L Ni, Q Yu, R You, C Chen, B Peng - Current Issues in Molecular Biology, 2023 - mdpi.com
Disulfidptosis is a newly discovered cellular programmed cell death mode. Presently, a
considerable number of genes related to disulfidptosis remain undiscovered, and its …

Identification of disulfidptosis-related genes with immune infiltration in hepatocellular carcinoma

X Li, S Liu, Y Li, X Cai, S Zhang, Z Xie - Heliyon, 2023 - cell.com
Hepatocellular carcinoma (HCC) is a common malignant primary tumor that is usually
diagnosed at an advanced stage; thus, there is an urgent need for efficient and sensitive …

[HTML][HTML] Molecular subtypes of disulfidptosis-regulated genes and prognosis models for predicting prognosis, tumor microenvironment infiltration, and therapeutic …

J Qu, H Guan, Q Zheng, F Sun - International Journal of Biological …, 2024 - Elsevier
Disulfidptosis, a recently identified mode of cellular demise marked by excess SLC7A11-
reliant cystine, has been proved to affect the development and resilience of tumor cells …

Disulfidptosis classification of hepatocellular carcinoma reveals correlation with clinical prognosis and immune profile

T Wang, K Guo, D Zhang, H Wang, J Yin, H Cui… - International …, 2023 - Elsevier
A new mode of cell death, disulfidptosis, has been discovered. Clinical prognostic
significance of disulfidptosis related pattern in hepatocellular carcinoma (HCC). In this study …

[HTML][HTML] Identification and characterization of a novel molecular classification based on disulfidptosis-related genes to predict prognosis and immunotherapy efficacy in …

L Yang, W Zhang, Y Yan - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
Background: Disulfidptosis has been discovered as a mechanism of cell death mediating by
SLC7A11. Nonetheless, little is known about the relationship between disulfidptosis-related …