This review gives a brief account of the main processes of lens development, including
induction, morphogenesis, differentiation and growth. It describes what is known about the …

This book provides a comprehensive view of research in lens developmental biology,
emphasising technical and molecular breakthroughs. Elucidation of the mechanisms that …

Lens-cell differentiation occurs at a fairly early stage of embryogenesis and results in very
simple tissue architecture. These features allow the embryonic lens to provide a paradigm of …

Millions are rendered blind or exhibit visual impairment due to pathologies of the lens of the
eye. Lens research therefore addresses the direct need to gain insights into the cellular and …

In this paper, the more recent literature pertaining to differentiation in the developing
vertebrate lens is reviewed in relation to previous work. The literature reviewed reveals that …

The factors that regulate the size of organs to ensure that they fit within an organism are not
well understood. A simple organ, the ocular lens serves as a useful model with which to …

The eye and lens represent excellent models to understand embryonic development at
cellular and molecular levels. Initial 3D formation of the eye depends on a reciprocal …

Embryologists at the turn of the century discovered the process of embryonic induction while
investigating the mechanisms of lens determination. The simple view of lens induction from …

This book describes the molecular biology and evolution of the crystallins, the characteristic
structural proteins of the eye lens, set in the overall context of the evolution of eyes. The …

The ocular lens is a model system for understanding important aspects of embryonic
development, such as cell specification and the spatiotemporally controlled formation of a …