DNA methylation is an epigenetic mechanism regulating gene expression. Changes in DNA
methylation were suggested to be useful biomarkers for diagnosis, and for the determination …

Since genetic and epigenetic alterations influence the development of colorectal cancer
(CRC), huge potential lies in the use of DNA methylation as biomarkers to improve the …

Colorectal cancer (CRC) is the second leading cause of cancer death worldwide that is
attributed to gradual long‐term accumulation of both genetic and epigenetic changes. To …

Abstract Each year, almost 4.1 million people are diagnosed with gastrointestinal (GI)
cancers. Due to late detection of this disease, the mortality is high, causing approximately 3 …

Colorectal cancer (CRC) is one of the most common cancer worldwide and results from the
accumulation of mutations and epimutations in colonic mucosa cells ultimately leading to …

Objective: Detection of aberrant methylated genes in feces has been developed as an early
screening method for colorectal cancer. The aim of this study was to probe the methylation …

The original theory of the multi-step process of colorectal cancer (CRC), suggesting that the
disease resulted from the accumulation of mutations in oncogenes and tumor suppressor …

Colorectal cancer (CRC) arises as a consequence of the accumulation of genetic and
epigenetic alterations in colonic epithelial cells during neoplastic transformation. Epigenetic …

Colorectal cancer (CRC) is the third most common type of cancer and is responsible for 9%
of cancer deaths in both men and women in the USA for 2013. It is a heterogenous disease …

Abstract Changes in DNA methylation, whether hypo‐or hypermethylation, have been
shown to be associated with the progression of colorectal cancer. Methylation changes …