A review of single-cell RNA-Seq annotation, integration, and cell–cell communication

C Cheng, W Chen, H Jin, X Chen - Cells, 2023 - mdpi.com
Single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool for investigating
cellular biology at an unprecedented resolution, enabling the characterization of cellular …

Biological and medical importance of cellular heterogeneity deciphered by single-cell RNA sequencing

RK Gupta, J Kuznicki - Cells, 2020 - mdpi.com
The present review discusses recent progress in single-cell RNA sequencing (scRNA-seq),
which can describe cellular heterogeneity in various organs, bodily fluids, and pathologies …

Single-cell RNA sequencing and its combination with protein and DNA analyses

JR Choi, KW Yong, JY Choi, AC Cowie - Cells, 2020 - mdpi.com
Heterogeneity in cell populations poses a significant challenge for understanding complex
cell biological processes. The analysis of cells at the single-cell level, especially single-cell …

Single-cell RNA sequencing technology landscape in 2023

HQ Qu, C Kao, H Hakonarson - Stem Cells, 2024 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) has revolutionized our understanding of cellular
heterogeneity and the dynamics of gene expression, bearing profound significance in stem …

Identifying cell types to interpret scRNA-seq data: how, why and more possibilities

Z Wang, H Ding, Q Zou - Briefings in functional genomics, 2020 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) has generated numerous data and renewed our
understanding of biological phenomena at the cellular scale. Identification of cell types has …

Data analysis guidelines for single-cell RNA-seq in biomedical studies and clinical applications

M Su, T Pan, QZ Chen, WW Zhou, Y Gong, G Xu… - Military Medical …, 2022 - Springer
The application of single-cell RNA sequencing (scRNA-seq) in biomedical research has
advanced our understanding of the pathogenesis of disease and provided valuable insights …

scRNASeqDB: a database for RNA-Seq based gene expression profiles in human single cells

Y Cao, J Zhu, P Jia, Z Zhao - Genes, 2017 - mdpi.com
Single-cell RNA sequencing (scRNA-Seq) is rapidly becoming a powerful tool for high-
throughput transcriptomic analysis of cell states and dynamics at the single cell level. Both …

Experimental considerations for single-cell RNA sequencing approaches

QH Nguyen, N Pervolarakis, K Nee… - Frontiers in cell and …, 2018 - frontiersin.org
Single-cell transcriptomic technologies have emerged as powerful tools to explore cellular
heterogeneity at the resolution of individual cells. Previous scientific knowledge in cell …

ASAP: a web-based platform for the analysis and interactive visualization of single-cell RNA-seq data

V Gardeux, FPA David, A Shajkofci, PC Schwalie… - …, 2017 - academic.oup.com
Motivation Single-cell RNA-sequencing (scRNA-seq) allows whole transcriptome profiling of
thousands of individual cells, enabling the molecular exploration of tissues at the cellular …

From multitude to singularity: An up-to-date overview of scRNA-seq data generation and analysis

G Carangelo, A Magi, R Semeraro - Frontiers in Genetics, 2022 - frontiersin.org
Single cell RNA sequencing (scRNA-seq) is today a common and powerful technology in
biomedical research settings, allowing to profile the whole transcriptome of a very large …