The host epigenetic landscape rapidly changes during SARS-CoV-2 infection, and evidence
suggest that severe COVID-19 is associated with durable scars to the epigenome …

The global pandemic caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is a highly pathogenic RNA virus causing coronavirus disease 2019 (COVID …

Single-cell transcriptome studies have revealed immune dysfunction in COVID-19 patients,
including lymphopenia, T cell exhaustion, and increased levels of pro-inflammatory …

Background There are no prior reports that compare differentially methylated regions of DNA
in blood samples from COVID-19 patients to samples collected before the SARS-CoV-2 …

SARS-CoV-2 infection can cause an inflammatory syndrome (COVID-19) leading, in many
cases, to bilateral pneumonia, severe dyspnea, and in~ 5% of these, death. DNA …

Background Understanding the molecular basis of susceptibility factors to the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a global health imperative. It …

DNA methylation comprises a cumulative record of lifetime exposures superimposed on
genetically determined markers. Little is known about methylation dynamics in humans …

Immune cell-type composition changes with age, potentially weakening the response to
infectious diseases. Profiling epigenetics marks of immune cells can help us understand the …

Recent studies have shown that methylation changes identified in blood cells of COVID-19
patients have a potential to be used as biomarkers of SARS-CoV-2 infection outcomes …

Background Since the onset of the SARS-CoV-2 pandemic, most clinical testing has focused
on RT-PCR. Host epigenome manipulation post coronavirus infection,–suggests that DNA …