Previous studies of early life trauma suggest that in addition to its emotional impact,
exposure to early life stress (ELS) is associated with alterations in brain structure. However …

The early postnatal period is a highly sensitive time period for the developing brain, both in
humans and rodents. During this time window, exposure to adverse experiences can …

Previous studies have shown that exposure to early life stress (ELS) is associated with
reduced volume of brain regions critical for information processing, memory and emotional …

Background Adversity experiences (AEs) are major risk factors for psychiatric illness, and
ample evidence suggests that adversity‐related changes in brain structure enhance this …

Importance Adverse childhood experiences (ACEs) have been associated with poor mental
and physical health outcomes. However, the mechanism of this effect, critical to enhancing …

Adversity in early childhood exerts an enduring impact on mental and physical health,
academic achievement, lifetime productivity, and the probability of interfacing with the …

Objectives To determine whether there is a relationship between early life adversity (ELA)
and biological parameters known to predict health risks and to examine the extent to which …

Abuse, neglect, exposure to violence, and other forms of early life adversity (ELA) are
incredibly common and significantly impact physical and mental development. While …

Early-life stress (ELS) or adversity, particularly in the form of childhood neglect and abuse, is
associated with poor mental and physical health outcomes in adulthood. However, whether …

Early life stress (ELS) induces long-term phenotypic adaptations that contribute to increased
vulnerability to a host of neuropsychiatric disorders. Epigenetic mechanisms, including DNA …