Most developmental work regards adverse developmental experiences as forces that
undermine well-being. Here, I present an alternative—or complementary—view …

Early-life stress (ELS) is associated with increased vulnerability to mental disorders. The
basolateral amygdala (BLA) plays a critical role in fear conditioning and is extremely …

In adulthood, stress exposure and genetic risk heighten psychological vulnerability by
accelerating neurobiological senescence. To investigate whether molecular and brain …

Importance A growing body of literature suggests that exposure to early-life adversity (ELA)
is associated with accelerated biological aging, offering 1 mechanism through which ELA …

Importance Early adversity is an important risk factor that relates to internalizing symptoms
and altered brain structure. Objective To assess the direct effects of early adversity and child …

For children reared in institutions for orphaned or abandoned children, multiple aspects of
the early environment deviate from species-typical experiences, which may lead to …

The early life environment markedly influences brain and behavioral development, with
adverse experiences associated with increased risk of anxiety and depressive phenotypes …

Background A large body of research supports the deleterious effects of adverse childhood
experiences (ACEs) on disease susceptibility and health for both the exposed individual and …

Disruptions in early life care, including neglect, extreme poverty, and trauma, influence
neural development and increase the risk for and severity of pathology. Significant sex …

Exposure to early life stress (ELS), such as childhood abuse and neglect is a well
established major risk factor for developing psychiatric and behavioral disorders later in life …