Enhanced emotion regulation capacity and its neural substrates in those exposed to moderate childhood adversity
S Schweizer, ND Walsh, J Stretton… - Social cognitive and …, 2016 - academic.oup.com
Individuals exposed to childhood adversities (CA) present with emotion regulation (ER)
difficulties in later life, which have been identified as risk and maintenance factors for …
difficulties in later life, which have been identified as risk and maintenance factors for …
The mediating role of allostatic load in the relationship between early life adversity and cognitive function across the adult lifespan
Early life adversity is consequential for poor cognitive health in mid to late-life. Early life
adversity is associated with higher allostatic load, a biological indicator of physiological …
adversity is associated with higher allostatic load, a biological indicator of physiological …
[HTML][HTML] The effect of early life stress on adult psychiatric disorders
SD Targum, CB Nemeroff - Innovations in clinical neuroscience, 2019 - ncbi.nlm.nih.gov
There is a crisis of early childhood maltreatment in the United States. In 2012, the United
States Department of Health and Human Services noted 3.4 million referrals to childhood …
States Department of Health and Human Services noted 3.4 million referrals to childhood …
Interactive impact of childhood maltreatment, depression, and age on cortical brain structure: mega-analytic findings from a large multi-site cohort
BackgroundChildhood maltreatment (CM) plays an important role in the development of
major depressive disorder (MDD). The aim of this study was to examine whether CM severity …
major depressive disorder (MDD). The aim of this study was to examine whether CM severity …
Impact of dimensions of early adversity on adult health and functioning: A 2-decade, longitudinal study
EW McGinnis, M Sheridan… - Development and …, 2022 - cambridge.org
Recent neurodevelopmental and evolutionary theories offer strong theoretical rationales
and some empirical evidence to support the importance of specific dimensions of early …
and some empirical evidence to support the importance of specific dimensions of early …
Reduced medial prefrontal cortex volume in adults reporting childhood emotional maltreatment
BACKGROUND: Childhood emotional maltreatment (CEM) has been associated with a
profound and enduring negative impact on behavioral and emotional functioning. Animal …
profound and enduring negative impact on behavioral and emotional functioning. Animal …
Childhood adversity impacts on brain subcortical structures relevant to depression
Childhood adversity plays an important role for development of major depressive disorder
(MDD). There are differences in subcortical brain structures between patients with MDD and …
(MDD). There are differences in subcortical brain structures between patients with MDD and …
Epigenetics of early-life adversity in youth: cross-sectional and longitudinal associations
Abstract Background Altered DNA methylation (DNAm) may be one pathway through which
early-life adversity (ELA) contributes to adverse mental and physical health outcomes. This …
early-life adversity (ELA) contributes to adverse mental and physical health outcomes. This …
Associations of early-life threat and deprivation with executive functioning in childhood and adolescence: a systematic review and meta-analysis
Importance Many studies have demonstrated an association between early-life adversity
(ELA) and executive functioning in children and adolescents. However, the aggregate …
(ELA) and executive functioning in children and adolescents. However, the aggregate …
Vulnerability and resilience to Alzheimer's disease: early life conditions modulate neuropathology and determine cognitive reserve
SL Lesuis, L Hoeijmakers, A Korosi… - Alzheimer's research & …, 2018 - Springer
Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder with a
high prevalence among the elderly and a huge personal and societal impact. Recent …
high prevalence among the elderly and a huge personal and societal impact. Recent …