Adverse childhood experiences (ACEs) increase risk for depression at subsequent ages
and have been linked to accelerated biological aging. We hypothesize that accelerated …

Adverse childhood experiences have been consistently linked with physical and mental
health disorders in adulthood that may be mediated, in part, via the effects of such …

Adverse effects of psychological stress on physical and mental health, especially in older
age, are well documented. How perceived stress relates to the epigenetic clock measure …

Introduction Prior studies have shown inconsistent findings of an association between
depression and epigenetic aging. DNA methylation (DNAm) age acceleration can measure …

Background Research has suggested that 'risky'family processes have unforeseen negative
consequences for health later in life. The purpose of this study was to further understanding …

Objective This study tests associations of DNA methylation-based (DNAm) measures of
epigenetic age acceleration (EAA) with cross-sectional and longitudinal depressive …

Research examining the association between exposure to a wide range of adverse
childhood experiences (ACEs) and accelerated biological aging in older adults is limited …

Biomarkers developed from DNA methylation (DNAm) data are of growing interest as
predictors of health outcomes and mortality in older populations. However, it is unknown …

Child maltreatment is a major risk factor for both depressive and anxiety disorders. However,
many children exposed to maltreatment never meet diagnostic threshold for either disorder …

Background While numerous studies have documented the power of new generation
epigenetic clocks to predict morbidity and mortality, research regarding the causes of …