Objective To understand why children exposed to adverse psychosocial experiences are at
elevated risk for age-related disease, such as cardiovascular disease, by testing whether …

BACKGROUND: Retrospective studies show that childhood adversity is associated with
systemic inflammation in adulthood. Few prospective studies have examined whether …

Objective: The current study examined the prospective effects of exposure to stressful
conditions in early childhood on physical health in young adulthood, and explored …

Abstract Adverse Childhood Experiences (ACEs) are stressful and/or traumatic experiences
that occur during childhood. Research has demonstrated a link between ACEs and risk of …

Objective: Adverse events in childhood can indelibly influence adult health. While evidence
for this association has mounted, a fundamental set of questions about how to …

Background Children exposed to social adversity carry a greater risk of poor physical and
mental health into adulthood. This increased risk is thought to be due, in part, to …

We examined the joint contributions of self-reported adverse childhood experiences (ACEs)
and recent life events (RLEs) to inflammation at midlife, by testing 3 competing theoretical …

Early exposure to stress and adversity can have both immediate and lasting effects on
physical and psychological health. Critical periods have been identified in infancy, during …

Objective: There has been an increased interest in the role of the childhood social
environment in the etiology of adult diseases in recent years. The present study examines …

How do adverse childhood experiences get 'under the skin'and influence health outcomes
through the life-course? Research reviewed here suggests that adverse childhood …