The embryonic nervous system of Drosophila melanogaster derives from the neurogenic
ectoderm, which is subdivided into three distinct domains. Several key transcription factors …

Cell type specification during early nervous system development in Drosophila
melanogaster requires precise regulation of gene expression in time and space. Resolving …

During embryonic development of Drosophila melanogaster, the maternal-to-zygotic
transition (MZT) marks a significant and rapid turning point when zygotic transcription begins …

Embryonic development results in the production of distinct tissue types, and different cell
types within each tissue. A major goal of developmental biology is to uncover the “parts list” …

By the onset of morphogenesis, Drosophila embryos consist of about 6000 cells that express
distinct gene combinations. Here, we used single-cell sequencing of precisely staged …

A nuclear concentration gradient of the maternal transcription factor Dorsal establishes three
tissues across the dorsal–ventral axis of precellular Drosophila embryos: mesoderm …

Embryonic neurogenesis in Drosophila is a highly coordinated sequence of cell fate
decisions that bears many similarities to the development of the nervous system in …

The transformative events during early organismal development lay the foundation for body
formation and long-term phenotype. The rapid progression of events and the limited material …

Drosophila has long been a successful model organism in multiple biomedical fields. Spatial
gene expression patterns are critical for the understanding of complex pathways and …

Drosophila melanogaster is a powerful, long-standing model for metazoan development and
gene regulation. We profiled chromatin accessibility in almost 1 million and gene expression …