Bioinformatics analysis and prediction of Alzheimer's disease and alcohol dependence based on Ferroptosis-related genes

M Tian, J Shen, Z Qi, Y Feng, P Fang - Frontiers in aging …, 2023 - frontiersin.org
Background Alzheimer's disease (AD) is a neurodegenerative disease whose origins have
not been universally accepted. Numerous studies have demonstrated the relationship …

Exploring the key ferroptosis-related gene in the peripheral blood of patients with Alzheimer's disease and its clinical significance

X Wang, Y Tian, C Li, M Chen - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Introduction Alzheimer's disease (AD) is the most common type of dementia, and there is
growing evidence suggesting that ferroptosis is involved in its pathogenesis. In this study …

Discovery and validation of Ferroptosis-related molecular patterns and immune characteristics in Alzheimer's disease

YJ He, L Cong, SL Liang, X Ma, JN Tian… - Frontiers in aging …, 2022 - frontiersin.org
Background To date, the pathogenesis of Alzheimer's disease is still not fully elucidated.
Much evidence suggests that Ferroptosis plays a crucial role in the pathogenesis of AD, but …

Identification of ferroptosis-related genes in Alzheimer's disease based on bioinformatic analysis

Y Wang, G Chen, W Shao - Frontiers in Neuroscience, 2022 - frontiersin.org
Introduction Alzheimer's disease (AD) is the most prevalent cause of dementia, and
emerging evidence suggests that ferroptosis is involved in the pathological process of AD …

Identification ferroptosis-related hub genes and diagnostic model in Alzheimer's disease

H Zhao, J Wang, Z Li, S Wang, G Yu… - Frontiers in Molecular …, 2023 - frontiersin.org
Background Ferroptosis is a newly defined form of programmed cell death and plays an
important role in Alzheimer's disease (AD) pathology. This study aimed to integrate …

Machine learning models identify ferroptosis-related genes as potential diagnostic biomarkers for Alzheimer's disease

Y Deng, Y Feng, Z Lv, J He, X Chen, C Wang… - Frontiers in Aging …, 2022 - frontiersin.org
Alzheimer's disease (AD) is a complex, and multifactorial neurodegenerative disease.
Previous studies have revealed that oxidative stress, synaptic toxicity, autophagy, and …

Ferroptosis-related biomarkers for Alzheimer's disease: Identification by bioinformatic analysis in hippocampus

B Wang, C Fu, Y Wei, B Xu, R Yang, C Li… - Frontiers in Cellular …, 2022 - frontiersin.org
Background Globally, Alzheimer's Disease (AD) accounts for the majority of dementia,
making it a public health concern. AD treatment is limited due to the limited understanding of …

[HTML][HTML] A Bioinformatics Perspective on the Dysregulation of Ferroptosis and Ferroptosis-related Immune Cell Infiltration in Alzheimer's Disease

L Zhang, J Fang, Z Tang, Y Luo - International Journal of Medical …, 2022 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is the most prevalent dementia worldwide, but its pathophysiology
and molecular events remain unknown. Herein, we first analyzed the differential expression …

[HTML][HTML] The Construction and Validation of a Novel Ferroptosis-Related Gene Signature in Parkinson's Disease

T Liu, H Wu, J Wei - International Journal of Molecular Sciences, 2023 - mdpi.com
As a newly discovered regulated cell death mode, ferroptosis is associated with the
development of Parkinson's disease (PD) and has attracted much attention. Nonetheless …

Genetic markers associated with ferroptosis in Alzheimer's disease

Y Sun, Y Xiao, Q Tang, W Chen, L Lin - Frontiers in Aging …, 2024 - frontiersin.org
Objective Ferroptosis is implicated in the pathogenesis of neurodegenerative disorders such
as Alzheimer's disease, Parkinson's disease, and vascular dementia, implying that it may …