The process of neurogenesis includes neural stem cell proliferation, fate specification,
young neuron migration, neuronal maturation, and functional integration into existing …

Epigenetic regulation represents a fundamental mechanism to maintain cell‐type‐specific
gene expression during development and serves as an essential mediator to interface the …

The cellular basis of adult neurogenesis is neural stem cells residing in restricted areas of
the adult brain. These cells self-renew and are multipotent. The maintenance of “stemness” …

Epigenetic mechanisms regulate cell differentiation during embryonic development and also
serve as important interfaces between genes and the environment in adulthood …

Epigenetic mechanisms convey information above and beyond the sequence of DNA, so it is
predicted that they are critical in the complex regulation of brain development and explain …

During embryonic brain development, neural progenitor/stem cells (NPCs) sequentially give
rise to different subtypes of neurons and glia via a highly orchestrated process. To …

Neural stem cells (NSCs) have the ability to self-renew and give rise to neurons and glial
cells (astrocytes and oligodendrocytes) in the mammalian central nervous system. This …

The recent years have witnessed an exponential growth in the knowledge of epigenetic
mechanisms, and piling evidence now links DNA methylation and histone modifications with …

In mature, differentiated neurons in the central nervous system (CNS), epigenetic
mechanisms—including DNA methylation, histone modification, and regulatory noncoding …

Neural development requires the orchestration of dynamic changes in gene expression to
regulate cell fate decisions. This regulation is heavily influenced by epigenetics, heritable …