The health of an organism is orchestrated by a multitude of molecular and biochemical
networks responsible for ensuring homeostasis within cells and tissues. However, upon …

Aging and longevity are controlled by a multiplicity of molecular and cellular signaling
events that interface with environmental factors to maintain cellular homeostasis. Modulation …

Aging is a fundamental biological process accompanied by a general decline in tissue
function. Indeed, as the lifespan increases, age-related dysfunction, such as cognitive …

Ageing is defined by the loss of functional reserve over time, leading to a decreased
capacity to maintain homeostasis under stress and increased risk of morbidity and mortality …

Molecular and cellular networks implicated in aging depend on a multitude of proteins that
collectively mount adaptive and contingent metabolic responses to environmental …

Aging is a gradual and irreversible pathophysiological process. It presents with declines in
tissue and cell functions and significant increases in the risks of various aging-related …

Ageing is driven by the inexorable and stochastic accumulation of damage in biomolecules
vital for proper cellular function. Although this process is fundamentally haphazard and …

Aging is characterized by a progressive loss of physiological integrity, leading to impaired
function and increased vulnerability to death. This deterioration is the primary risk factor for …

Aging is the single largest risk factor for many debilitating conditions, including heart
diseases, stroke, cancer, diabetes, and neurodegenerative disorders. Although far from …

Human aging and longevity are complex and multi-factorial traits that result from a
combination of environmental, genetic, epigenetic and stochastic factors, each contributing …