Individuals with serious mental disorders (SMDs) die at an earlier average age, even after
controlling for suicide1. They are also at increased risk for developing somatic diseases that …

We define and discuss several proposed biological aging markers that have been examined
in SMDs, we review the most recent findings, and we conclude with opinions regarding the …

Structural brain abnormalities are central to schizophrenia (SZ), but it remains unknown
whether they are linked to dysmaturational processes crossing diagnostic boundaries …

The notion that mental suffering can accelerate aging is widespread across cultures and
eras. This notion has been depicted widely by folklore legends and literary characters …

There is an old Indian saying:“If we are lucky, we will not be poor; if we are lucky, we will not
be disabled; but if we are lucky, we will live to be old.” Indeed, as the average lifespan in …

Background Serious mental illnesses may be characterized by accelerated biological aging,
and over the last years the research on the topic has been stimulated by studies exploring …

Background Schizophrenia is associated with increased risk of developing multiple aging-
related diseases, including metabolic, respiratory, and cardiovascular diseases, and …

Background: Schizophrenia is associated with increased physical morbidity and early
mortality, suggesting that the aging process may be accelerated in schizophrenia. However …

Patterns of accelerated aging have been reported in severe psychiatric disorders and are
hypothesized to underlie many poor health outcomes, including higher rates of chronic …

Schizophrenia patients show signs of accelerated aging in cognitive and physiological
domains. Both schizophrenia and accelerated aging, as measured by MRI brain images and …