cpc-2, a new locus involved in general control of amino acid synthetic enzymes in Neurospora crassa

D Krüger, J Koch, IB Barthelmess - Current genetics, 1990 - Springer
In Neurospora crassa starvation for single amino acids leads to derepression of enzymes in
many amino acid synthetic pathways. Regulation occurs at the level of transcription via …

Restricted activation of general amino acid control under conditions of glutamine limitation in Neurospora crassa

J Kolanus, J Michalczyk, HJ Flint… - Molecular and General …, 1990 - Springer
In Neurospora crassa limitation for single amino acids normally results in increased
formation of enzymes required for amino acid synthesis via 'general amino acid control' …

Determination of the inactivating alterations in two mutant alleles of the Neurospora crassa cross-pathway control gene cpc-1.

JL Paluh, M Plamann, D Krüger, IB Barthelmess… - Genetics, 1990 - academic.oup.com
Abstract cpc-1 is the locus specifying what is believed to be the major trans-activating
transcription factor that regulates expression of amino acid biosynthetic genes subject to …

The range of amino acids whose limitation activates general amino-acid control in Neurospora crassa

IB Barthelmess, J Kolanus - Genetics Research, 1990 - cambridge.org
Several amino-acid synthetic enzymes, belonging to arginie, glutamine, leucine, lysine and
phenylalanine biosynthesis, respectively, were investigated under conditions of reduced …

Changes in gene expression elicited by amino acid limitation in Neurospora crassa strains having normal or mutant cross-pathway amino acid control

HJ Flint - Molecular and General Genetics MGG, 1985 - Springer
The effects of amino acid limitation on gene expression have been investigated in
Neurospora crassa strains carrying normal (cpc-1+) or mutant (cpc-1) alleles at a locus …

Cloning of the arg-12 gene of Neurospora crassa and regulation of its transcript via cross-pathway amino acid control

HJ Flint, J Wilkening - Molecular and General Genetics MGG, 1986 - Springer
The arg-12 locus of Neurospora crassa encodes ornithine carbamoyl transferase, which is
one of many amino acid synthetic enzymes whose activity is regulated through cross …

A lethal allele at the putative regulatory locus, cpc-1, of cross-pathway control in Neurospora crassa

IB Barthelmess - Molecular and General Genetics MGG, 1984 - Springer
A lethal allele at the putative regulatory locus, cpc-1, of cross-pathway control in Neurospora
crassa was discovered by genetic analysis. cpc-1 j-5 is viable only in the presence of a …

Regulation of amino acid synthetic enzymes in Neurospora crassa in the presence of high concentrations of amino acids

IB Barthelmess - Molecular and General Genetics MGG, 1986 - Springer
Ornithine carbamoyl transferase and leucine aminotransferase of Neurospora crassa
represent two of many amino acid synthetic enzymes which are regulated through cross …

cpc-1, the General Regulatory Gene for Genes of Amino Acid Biosynthesis in Neurospora crassa, Is Differentially Expressed during the Asexual Life Cycle

DJ Ebbole, JL Paluh, M Plamann… - … and cellular biology, 1991 - Taylor & Francis
CPC1, the principal regulatory protein required for cross-pathway control of amino acid
biosynthetic genes in Neurospora crassa, contains a domain similar to the DNA-binding …

Mutants affecting amino acid cross-pathway control in Neurospora crassa

IB Barthelmess - Genetics Research, 1982 - cambridge.org
Arginine-requiring mutants of Neurospora crassa were isolated using a strain partially
impaired in an enzyme of the arginine pathway (bradytroph). Among these, five strains were …