Aberrant DNA methylation has shown promise as a biomarker for the early detection of
cancer. To discover novel genes frequently methylated at an early stage in colorectal cancer …

Background Colorectal cancer (CRC) screening is the most efficient strategy to reduce
disease-related mortality. Frequent aberrant DNA methylation is known to occur in selected …

Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Early
detection of CRC can significantly reduce this mortality rate. Unfortunately, recommended …

Background Early detection plays an essential role to reduce colorectal cancer (CRC)
mortality. While current screening methods suffer from poor compliance, liquid biopsy-based …

Background There is an increasing demand for accurate biomarkers for early non-invasive
colorectal cancer detection. We employed a genome-scale marker discovery method to …

Colorectal cancer (CRC) is the second leading cause of cancer death worldwide that is
attributed to gradual long‐term accumulation of both genetic and epigenetic changes. To …

Background Colorectal polyp is known a precursor of colorectal cancer (CRC) that holds an
increased risk for progression to CRC. Circulating cell-free DNA (cfDNA) methylation has …

Colorectal cancer (CRC) is one of the most common and deadliest cancers worldwide.
Patient survival can be greatly improved if cancerous lesions are detected early. 1 Despite a …

Screening for early‐stage disease is vital for reducing colorectal cancer (CRC)‐related
mortality. Methylation of circulating tumor DNA has been previously used for various types of …

Colorectal cancer (CRC), the second leading cause of cancer mortality, constitutes a
significant global health burden. An accurate, noninvasive detection method for CRC as …