[HTML][HTML] Accelerated biological aging in COVID-19 patients
Chronological age is a risk factor for SARS-CoV-2 infection and severe COVID-19. Previous
findings indicate that epigenetic age could be altered in viral infection. However, the …
findings indicate that epigenetic age could be altered in viral infection. However, the …
[HTML][HTML] Evidence for biological age acceleration and telomere shortening in COVID-19 survivors
A Mongelli, V Barbi, M Gottardi Zamperla… - International journal of …, 2021 - mdpi.com
The SARS-CoV-2 infection determines the COVID-19 syndrome characterized, in the worst
cases, by severe respiratory distress, pulmonary and cardiac fibrosis, inflammatory cytokine …
cases, by severe respiratory distress, pulmonary and cardiac fibrosis, inflammatory cytokine …
[HTML][HTML] Longitudinal study of DNA methylation and epigenetic clocks prior to and following test-confirmed COVID-19 and mRNA vaccination
APS Pang, AT Higgins-Chen, F Comite, I Raica… - Frontiers in …, 2022 - frontiersin.org
The host epigenetic landscape rapidly changes during SARS-CoV-2 infection, and evidence
suggest that severe COVID-19 is associated with durable scars to the epigenome …
suggest that severe COVID-19 is associated with durable scars to the epigenome …
[HTML][HTML] Severe COVID-19 is associated with molecular signatures of aging in the human brain
M Mavrikaki, JD Lee, IH Solomon, FJ Slack - Nature Aging, 2022 - nature.com
Abstract As coronavirus disease 2019 (COVID-19) and aging are both accompanied by
cognitive decline, we hypothesized that COVID-19 might lead to molecular signatures …
cognitive decline, we hypothesized that COVID-19 might lead to molecular signatures …
[HTML][HTML] Why does COVID-19 disproportionately affect older people?
AL Mueller, MS McNamara, DA Sinclair - Aging (albany NY), 2020 - ncbi.nlm.nih.gov
The severity and outcome of coronavirus disease 2019 (COVID-19) largely depends on a
patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23 …
patient's age. Adults over 65 years of age represent 80% of hospitalizations and have a 23 …
[HTML][HTML] Pulmonary infection by SARS-CoV-2 induces senescence accompanied by an inflammatory phenotype in severe COVID-19: possible implications for viral …
K Evangelou, D Veroutis, K Paschalaki… - European …, 2022 - Eur Respiratory Soc
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of
the respiratory system can progress to a multisystemic disease with aberrant inflammatory …
the respiratory system can progress to a multisystemic disease with aberrant inflammatory …
Cellular senescence as a potential mediator of COVID‐19 severity in the elderly
J Nehme, M Borghesan, S Mackedenski, TG Bird… - Aging cell, 2020 - Wiley Online Library
SARS‐CoV‐2 is a novel betacoronavirus which infects the lower respiratory tract and can
cause coronavirus disease 2019 (COVID‐19), a complex respiratory distress syndrome …
cause coronavirus disease 2019 (COVID‐19), a complex respiratory distress syndrome …
Biomarkers of ageing and frailty may predict COVID-19 severity
KJ Wanhella, C Fernandez-Patron - Ageing research reviews, 2022 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) is caused by the novel coronavirus, Severe
Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)-the culprit of an ongoing …
Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)-the culprit of an ongoing …
[HTML][HTML] COVID-19 severity is predicted by earlier evidence of accelerated aging
With no known treatments or vaccine, COVID-19 presents a major threat, particularly to older
adults, who account for the majority of severe illness and deaths. The age-related …
adults, who account for the majority of severe illness and deaths. The age-related …
COVID‐19 is an emergent disease of aging
COVID‐19 is an ongoing pandemic caused by the SARS‐CoV‐2 coronavirus that poses one
of the greatest challenges to public health in recent years. SARS‐CoV‐2 is known to …
of the greatest challenges to public health in recent years. SARS‐CoV‐2 is known to …