[HTML][HTML] Re-analysis of SARS-CoV-2-infected host cell proteomics time-course data by impact pathway analysis and network analysis: a potential link with …

JO Bock, I Ortea - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), caused by an outbreak of the severe acute
respiratory syndrome-coronavirus 2 (SARS-CoV-2) in Wuhan, China, has led to an …

[HTML][HTML] Age-related DNA methylation changes are sex-specific: a comprehensive assessment

I Yusipov, MG Bacalini, A Kalyakulina… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
The existence of a sex gap in human health and longevity has been widely documented.
Autosomal DNA methylation differences between males and females have been reported …

[HTML][HTML] Alzheimer's and Parkinson's diseases predict different COVID-19 outcomes: a UK Biobank study

Y Yu, M Travaglio, R Popovic, NS Leal, LM Martins - Geriatrics, 2021 - mdpi.com
In December 2019, a coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2), began infecting humans, causing a novel disease, coronavirus disease 19 (COVID …

Aging & COVID-19 susceptibility, disease severity, and clinical outcomes: The role of entangled risk factors

M Farshbafnadi, SK Zonouzi, M Sabahi… - Experimental …, 2021 - Elsevier
Abstract The emergence of Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-
2) in late 2019 has been associated with a high rate of mortality and morbidity. It has been …

Association between COVID‐19 and telomere length: a bidirectional Mendelian randomization study

D Huang, S Lin, J He, Q Wang… - Journal of medical …, 2022 - Wiley Online Library
Several traditional observational studies suggested an association between COVID‐19 and
leukocyte telomere length (LTL), a biomarker for biological age. However, whether there …

COVID-19 and crosstalk with the hallmarks of aging

S Salimi, JM Hamlyn - The Journals of Gerontology: Series A, 2020 - academic.oup.com
Within the past several decades, the emergence of new viral diseases with severe health
complications and mortality is evidence of an age-dependent, compromised bodily response …

[HTML][HTML] Short telomeres increase the risk of severe COVID-19

A Froidure, M Mahieu, D Hoton, PF Laterre… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Telomeres are non-coding DNA sequences that protect chromosome ends and shorten with
age. Short telomere length (TL) is associated with chronic diseases and …

A human circulating immune cell landscape in aging and COVID-19

Y Zheng, X Liu, W Le, L Xie, H Li, W Wen, S Wang… - Protein & …, 2020 - academic.oup.com
Age-associated changes in immune cells have been linked to an increased risk for infection.
However, a global and detailed characterization of the changes that human circulating …

[HTML][HTML] SARS-CoV-2 infection triggers paracrine senescence and leads to a sustained senescence-associated inflammatory response

S Tsuji, S Minami, R Hashimoto, Y Konishi, T Suzuki… - Nature aging, 2022 - nature.com
Reports of post-acute COVID-19 syndrome, in which the inflammatory response persists
even after SARS-CoV-2 has disappeared, are increasing, but the underlying mechanisms of …

[HTML][HTML] Single-cell transcriptomics reveal a unique memory-like NK cell subset that accumulates with ageing and correlates with disease severity in COVID-19

C Guo, M Wu, B Huang, R Zhao, L Jin, B Fu, P Wang… - Genome medicine, 2022 - Springer
Background Natural killer (NK) cells are innate lymphoid cells that mediate antitumour and
antiviral responses. However, very little is known about how ageing influences human NK …