[HTML][HTML] Exploiting the molecular basis of age and gender differences in outcomes of SARS-CoV-2 infections
Motivation: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
(coronavirus disease, 2019; COVID-19) is associated with adverse outcomes in patients. It …
(coronavirus disease, 2019; COVID-19) is associated with adverse outcomes in patients. It …
[HTML][HTML] From causes of aging to death from COVID-19
MV Blagosklonny - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
COVID-19 is not deadly early in life, but mortality increases exponentially with age, which is
the strongest predictor of mortality. Mortality is higher in men than in women, because men …
the strongest predictor of mortality. Mortality is higher in men than in women, because men …
[HTML][HTML] DNA methylation biomarkers in aging and age-related diseases
Recent research efforts provided compelling evidence of genome-wide DNA methylation
alterations in aging and age-related disease. It is currently well established that DNA …
alterations in aging and age-related disease. It is currently well established that DNA …
[HTML][HTML] Probing long COVID through a proteomic lens: a comprehensive two-year longitudinal cohort study of hospitalised survivors
X Gu, S Wang, W Zhang, C Li, L Guo, Z Wang, H Li… - …, 2023 - thelancet.com
Background As a debilitating condition that can impact a whole spectrum of people and
involve multi-organ systems, long COVID has aroused the most attention than ever …
involve multi-organ systems, long COVID has aroused the most attention than ever …
[HTML][HTML] Epigenetic and transcriptomic reprogramming in monocytes of severe COVID-19 patients reflects alterations in myeloid differentiation and the influence of …
G Godoy-Tena, A Barmada, O Morante-Palacios… - Genome Medicine, 2022 - Springer
Background COVID-19 manifests with a wide spectrum of clinical phenotypes, ranging from
asymptomatic and mild to severe and critical. Severe and critical COVID-19 patients are …
asymptomatic and mild to severe and critical. Severe and critical COVID-19 patients are …
[HTML][HTML] Age-related morbidity and mortality among patients with COVID-19
SJ Kang, SI Jung - Infection & chemotherapy, 2020 - ncbi.nlm.nih.gov
Abstract On March 11, 2020, the World Health Organization declared coronavirus disease
(COVID-19), caused by the novel coronavirus severe acute respiratory syndrome …
(COVID-19), caused by the novel coronavirus severe acute respiratory syndrome …
[HTML][HTML] Dynamic DNA methylation during aging: a “prophet” of age-related outcomes
FH Xiao, HT Wang, QP Kong - Frontiers in genetics, 2019 - frontiersin.org
The biological markers of aging used to predict physical health status in older people are of
great interest. Telomere shortening, which occurs during the process of cell replication, was …
great interest. Telomere shortening, which occurs during the process of cell replication, was …
[HTML][HTML] Single-cell transcriptomic atlas of primate cardiopulmonary aging
Aging is a major risk factor for many diseases, especially in highly prevalent
cardiopulmonary comorbidities and infectious diseases including Coronavirus Disease …
cardiopulmonary comorbidities and infectious diseases including Coronavirus Disease …
[HTML][HTML] Epigenome-wide association study of COVID-19 severity with respiratory failure
MC de Moura, V Davalos, L Planas-Serra… - …, 2021 - thelancet.com
Background Patients infected with the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), responsible for the coronavirus disease 2019 (COVID-19), exhibit a wide …
(SARS-CoV-2), responsible for the coronavirus disease 2019 (COVID-19), exhibit a wide …
Causal effect of COVID‐19 on Alzheimer's disease: a Mendelian randomization study
A Baranova, H Cao, F Zhang - Journal of medical virology, 2023 - Wiley Online Library
It was reported that severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
infection may cause brain size reduction and cognitive decline. Whether COVID‐19 may …
infection may cause brain size reduction and cognitive decline. Whether COVID‐19 may …