COVID-19 and quarantine, a catalyst for ageism
N Barth, J Guyot, SA Fraser, M Lagacé… - Frontiers in public …, 2021 - frontiersin.org
In February 2021, France had more than 76,000 deaths due to COVID-19 and older adults
were heavily affected. Most measures taken to reduce the impact of COVID-19 (quarantine …
were heavily affected. Most measures taken to reduce the impact of COVID-19 (quarantine …
COVID-19 in older adults
A Nanda, NVRK Vura, S Gravenstein - Aging clinical and experimental …, 2020 - Springer
The advent of the SARS-CoV-2 and COVID-19 pandemic has generated a lot of publications
at a rapid pace. We know that older adults disproportionately suffer the most severe of …
at a rapid pace. We know that older adults disproportionately suffer the most severe of …
[HTML][HTML] COVID-19, virology and geroscience: a perspective
C Vellas, P Delobel, PDS Barreto, J Izopet - The journal of nutrition, health …, 2020 - Elsevier
A new coronavirus, called SARS-CoV-2, was identified in Wuhan, China, in December 2019.
The SARS-CoV-2 spread very rapidly, causing a global pandemic, Coronavirus Disease …
The SARS-CoV-2 spread very rapidly, causing a global pandemic, Coronavirus Disease …
DNA methylation and healthy human aging
The process of aging results in a host of changes at the cellular and molecular levels, which
include senescence, telomere shortening, and changes in gene expression. Epigenetic …
include senescence, telomere shortening, and changes in gene expression. Epigenetic …
Age-associated SARS-CoV-2 breakthrough infection and changes in immune response in a mouse model
Older individuals are at higher risk of SARS-CoV-2 infection and severe outcomes, but the
underlying mechanisms are incompletely understood. In addition, how age modulates SARS …
underlying mechanisms are incompletely understood. In addition, how age modulates SARS …
Shorter leukocyte telomere length is associated with adverse COVID-19 outcomes: a cohort study in UK Biobank
Background Older age is the most powerful risk factor for adverse coronavirus disease-19
(COVID-19) outcomes. It is uncertain whether leucocyte telomere length (LTL), previously …
(COVID-19) outcomes. It is uncertain whether leucocyte telomere length (LTL), previously …
Besides population age structure, health and other demographic factors can contribute to understanding the COVID-19 burden
MR Nepomuceno, E Acosta… - Proceedings of the …, 2020 - National Acad Sciences
An insightful paper by Dowd et al.(1) highlights the importance of demography for analyzing
coronavirus disease 2019 (COVID-19)–related mortality. The authors underscore the role of …
coronavirus disease 2019 (COVID-19)–related mortality. The authors underscore the role of …
[PDF][PDF] Cell-free DNA tissues of origin by methylation profiling reveals significant cell, tissue, and organ-specific injury related to COVID-19 severity
Summary Background Coronavirus disease 2019 (COVID-19) primarily affects the lungs, but
evidence of systemic disease with multi-organ involvement is emerging. Here, we …
evidence of systemic disease with multi-organ involvement is emerging. Here, we …
Back to the future: epigenetic clock plasticity towards healthy aging
K Declerck, WV Berghe - Mechanisms of ageing and development, 2018 - Elsevier
Aging is the most important risk factor for major human lifestyle diseases, including cancer,
neurological and cardiometabolic disorders. Due to the complex interplay between genetics …
neurological and cardiometabolic disorders. Due to the complex interplay between genetics …
Immunosenescence exacerbates the COVID-19
Aging and senescence are complex processes associated with increased frailty (Calimport,
Bentley, & Stewart, 2019). Overall, many pathogens are more aggressive and prevalent in …
Bentley, & Stewart, 2019). Overall, many pathogens are more aggressive and prevalent in …