Although epigenetic processes have been linked to aging and disease in other systems, it is
not yet known whether they relate to reproductive aging. Recently, we developed a highly …

Background Age-associated DNA methylation changes provide a promising biomarker for
the aging process. While genome-wide DNA methylation profiles enable robust age …

DNA methylation plays an important role in development of disease and the process of
aging. In this study we examine DNA methylation at 476,366 sites throughout the genome of …

In humans, leukocyte telomere length (LTL) is positively correlated with lifespan and shorter
LTL is associated with increased risk of age-related disease. In this study we tested for …

All tissues of organisms will become old as time goes on. In recent years, epigenetic
investigations have found that there is a close correlation between DNA methylation and …

Background Smoking leads to the aging of organs. However, no studies have been
conducted to quantify the effect of smoking on the aging of respiratory organs and the aging …

The medical, public health, and scientific communities are grappling with monumental
imperatives to contain COVID‐19, develop effective vaccines, identify efficacious treatments …

DNA methylation aging clocks have become an invaluable tool in biogerontology research
since their inception in 2013. Today, a variety of machine learning approaches have been …

Aim of the study A vast majority of human malignancies are associated with ageing, and age
is a strong predictor of cancer risk. Recently, DNA methylation-based marker of ageing …

The ability to measure human aging from molecular profiles has practical implications in
many fields, including disease prevention and treatment, forensics, and extension of life …