[HTML][HTML] Computational assignment of cell-cycle stage from single-cell transcriptome data

A Scialdone, KN Natarajan, LR Saraiva, V Proserpio… - Methods, 2015 - Elsevier
The transcriptome of single cells can reveal important information about cellular states and
heterogeneity within populations of cells. Recently, single-cell RNA-sequencing has …

[HTML][HTML] A comparison of automatic cell identification methods for single-cell RNA sequencing data

T Abdelaal, L Michielsen, D Cats, D Hoogduin, H Mei… - Genome biology, 2019 - Springer
Background Single-cell transcriptomics is rapidly advancing our understanding of the
cellular composition of complex tissues and organisms. A major limitation in most analysis …

Putative cell type discovery from single-cell gene expression data

Z Miao, P Moreno, N Huang, I Papatheodorou… - Nature …, 2020 - nature.com
Abstract We present the Single-Cell Clustering Assessment Framework, a method for the
automated identification of putative cell types from single-cell RNA sequencing (scRNA-seq) …

scClassify: sample size estimation and multiscale classification of cells using single and multiple reference

Y Lin, Y Cao, HJ Kim, A Salim, TP Speed… - Molecular systems …, 2020 - embopress.org
Automated cell type identification is a key computational challenge in single‐cell RNA‐
sequencing (sc RNA‐seq) data. To capitalise on the large collection of well‐annotated sc …

Clustering single cells: a review of approaches on high-and low-depth single-cell RNA-seq data

V Menon - Briefings in functional genomics, 2018 - academic.oup.com
Advances in single-cell RNA-sequencing technology have resulted in a wealth of studies
aiming to identify transcriptomic cell types in various biological systems. There are multiple …

[HTML][HTML] Automatic cell type identification methods for single-cell RNA sequencing

B Xie, Q Jiang, A Mora, X Li - Computational and Structural Biotechnology …, 2021 - Elsevier
Single-cell RNA sequencing (scRNA-seq) has become a powerful tool for scientists of many
research disciplines due to its ability to elucidate the heterogeneous and complex cell-type …

[HTML][HTML] SciBet as a portable and fast single cell type identifier

C Li, B Liu, B Kang, Z Liu, Y Liu, C Chen, X Ren… - Nature …, 2020 - nature.com
Fast, robust and technology-independent computational methods are needed for supervised
cell type annotation of single-cell RNA sequencing data. We present SciBet, a supervised …

A comprehensive comparison of supervised and unsupervised methods for cell type identification in single-cell RNA-seq

X Sun, X Lin, Z Li, H Wu - Briefings in bioinformatics, 2022 - academic.oup.com
The cell type identification is among the most important tasks in single-cell RNA-sequencing
(scRNA-seq) analysis. Many in silico methods have been developed and can be roughly …

Evaluation of single-cell classifiers for single-cell RNA sequencing data sets

X Zhao, S Wu, N Fang, X Sun, J Fan - Briefings in bioinformatics, 2020 - academic.oup.com
Single-cell RNA sequencing (scRNA-seq) has been rapidly developing and widely applied
in biological and medical research. Identification of cell types in scRNA-seq data sets is an …

[HTML][HTML] SCSA: a cell type annotation tool for single-cell RNA-seq data

Y Cao, X Wang, G Peng - Frontiers in genetics, 2020 - frontiersin.org
Currently most methods take manual strategies to annotate cell types after clustering the
single-cell RNA sequencing (scRNA-seq) data. Such methods are labor-intensive and …