Aging is the biggest risk factor for developing Parkinson's disease (PD), the second most
common neurodegenerative disorder. Several animal models have been developed to …

Parkinson's disease (PD) ranks second among the most common neurodegenerative
diseases, characterized by progressive and selective loss of dopaminergic neurons. Various …

The pathogenesis of Parkinson's disease (PD) is closely interwoven with the process of
aging. Moreover, increasing evidence from human postmortem studies and from animal …

Background Parkinson's disease (PD) is characterized by dopaminergic neuronal loss in the
substantia nigra pars compacta and intracellular inclusions called Lewy bodies (LB). During …

Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by
motor and non-motor symptoms. More than 200 years after its first clinical description, PD …

Parkinson's disease (PD) is a common chronic progressive multifactorial neurodegenerative
disease. In most cases, PD develops as a sporadic idiopathic disease. However, in 10 …

Highlights•Focus on human cells, tissues and subjects needed to address gaps in
understanding PD.•Human iPSC studies can reveal the impact of genes and exposure on …

Neurological disorders can be modeled in animals so as to recreate specific pathogenic
events and behavioral outcomes. Parkinson's Disease (PD) is the second most common …

Parkinson's disease (PD) is the second most common neurodegenerative disease and
affects approximately 2–3% of the population over the age of 65. PD is characterised by the …

Neurological conditions such as traumatic brain injury, stroke, Parkinson's disease, epilepsy,
multiple sclerosis, and Alzheimer's disease are serious clinical problems that affect millions …