Integrated bioinformatics analysis of hub genes and pathways in anaplastic thyroid carcinomas

X Gao, J Wang, S Zhang - International journal of …, 2019 - Wiley Online Library
Anaplastic thyroid carcinoma (ATC) is a very rare malignancy; the pathogenesis of which is
still not fully understood. The aim of the present study was to identify hub genes and …

Identification of hub genes in anaplastic thyroid carcinoma: evidence from bioinformatics analysis

L Li, M Zhu, H Huang, J Wu… - Technology in cancer …, 2020 - journals.sagepub.com
Anaplastic thyroid carcinoma (ATC) is a rare type of thyroid cancer that results in fatal clinical
outcomes; the pathogenesis of this life-threatening disease has yet to be fully elucidated …

Identification of key candidate genes and pathways in anaplastic thyroid cancer by bioinformatics analysis

YG Ding, YL Ren, YS Xu, CS Wei, YB Zhang… - American journal of …, 2020 - Elsevier
Background Anaplastic thyroid carcinoma (ATC) is a refractory and poor prognosis tumor
Present study aimed to investigate the underlying biological functions and pathways …

Integrated analysis of transcriptome data revealed MMP3 and MMP13 as critical genes in anaplastic thyroid cancer progression

Y Ma, S Cang, G Li, Y Su, H Zhang… - Journal of Cellular …, 2019 - Wiley Online Library
To better understand the molecular mechanisms of anaplastic thyroid carcinoma (ATC), we
aimed to identify the hub genes specifically involved in ATC by integrated bioinformatics …

Identification and validation of novel genes in anaplastic thyroid carcinoma via bioinformatics analysis

S Wang, J Wu, C Guo, H Shang, J Yao… - Cancer Management …, 2020 - Taylor & Francis
Purpose The conventional interventions of anaplastic thyroid carcinoma (ATC) patients are
mainly through surgery, chemotherapy, and radiotherapy; however, it is hardly to improve …

[HTML][HTML] Bioinformatics analysis of key genes and latent pathway interactions based on the anaplastic thyroid carcinoma gene expression profile

Y Huang, Y Tao, X Li, S Chang, B Jiang… - Oncology …, 2017 - spandidos-publications.com
Anaplastic thyroid carcinoma (ATC) is an aggressive malignant disease in older adults with
a high mortality rate. The present study aimed to examine several key genes and pathways …

Identification of hub genes in thyroid carcinoma to predict prognosis by integrated bioinformatics analysis

Y Pan, L Wu, S He, J Wu, T Wang, H Zang - Bioengineered, 2021 - Taylor & Francis
The aim of this study was to identify hub genes closely related to the pathogenesis and
prognosis of thyroid carcinoma (THCA) by integrated bioinformatics analysis. In this study …

Integrated bioinformatics analysis of master regulators in anaplastic thyroid carcinoma

Z Pan, L Li, Q Fang, Y Qian, Y Zhang… - BioMed research …, 2019 - Wiley Online Library
Anaplastic thyroid carcinoma (ATC) is one of the most aggressive and rapidly lethal tumors.
However, limited advances have been made to prolong the survival and to reduce the …

The differences of regulatory networks between papillary and anaplastic thyroid carcinoma: an integrative transcriptomics study

Z Pan, L Li, Y Qian, X Ge, X Hu, Y Zhang… - Cancer biology & …, 2020 - Taylor & Francis
Background Unlike papillary thyroid cancer (PTC), anaplastic thyroid carcinoma (ATC) is
extremely aggressive and rapidly lethal without effective therapies. However, the differences …

[HTML][HTML] Integrated bioinformatics analysis and screening of hub genes in papillary thyroid carcinoma

R Fan, L Dong, P Li, X Wang, X Chen - Plos one, 2021 - journals.plos.org
Background With the increasing incidence of papillary thyroid carcinoma (PTC), PTC
continues to garner attention worldwide; however its pathogenesis remains to be elucidated …