[HTML][HTML] Influence of aging on deterioration of patients with COVID-19

L Pang, Y Liu, M Shen, J Ye, R Chen, Z Lan… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Aging is an important factor affecting the deterioration of patients with coronavirus disease
2019 (COVID-19). The aging and degeneration of various tissues and organs in the elderly …

The clinical characteristics and risk factors of severe COVID-19

J Hu, Y Wang - Gerontology, 2021 - karger.com
Objective: We aim to investigate the clinical characteristics and risk factors for the severe
cases of coronavirus disease 2019 (COVID-19) in comparison with the non-severe patients …

How can biology of aging explain the severity of COVID-19 in older adults

A Gallo, E Pero, S Pellegrino… - Clinics in Geriatric …, 2022 - geriatric.theclinics.com
In December 2019 a cluster of pneumonia caused by a previous unknown coronavirus,
SARS-CoV-2, was identified in Wuhan, China. 1 SARS-CoV-2 belongs to the subgenus of …

[HTML][HTML] Patho-physiology of aging and immune-senescence: possible correlates with comorbidity and mortality in middle-aged and old COVID-19 patients

S Farheen, S Agrawal, S Zubair, A Agrawal… - Frontiers in …, 2021 - frontiersin.org
During the last 2 years, the entire world has been severely devastated by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic (COVID-19) as it resulted in …

[HTML][HTML] An intrinsic connection between COVID-19 and aging

J Wang, JCJ Wei, F Dang, H Inuzuka - Acta Materia Medica, 2023 - ucl.scienceopen.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a rapidly
spreading outbreak of coronavirus disease 2019 (the COVID-19 pandemic). COVID-19 has …

[HTML][HTML] Comparison of clinical characteristics of COVID-19 between elderly patients and young patients: a study based on a 28-day follow-up

L Zhang, T Fan, S Yang, H Feng, B Hao, Z Lu… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
The number of corona virus disease 2019 cases is increasing rapidly. However, the
comparison of clinical characteristics between patients≥ 70 and those< 70 has not been …

The impact of aging and COVID-19 on our immune system: a high-resolution map from single cell analysis

J Yang, H Li - Protein & cell, 2020 - academic.oup.com
One key aspect of human aging is the dysregulation of the immune system. As we age, our
body's defense system weakens, leading to declined responses to infection by new …

Aging, inflammaging and immunosenescence as risk factors of severe COVID-19

AM Tizazu, HM Mengist, G Demeke - Immunity & Ageing, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused
by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is …

[HTML][HTML] How does SARS-CoV-2 targets the elderly patients? A review on potential mechanisms increasing disease severity

A Smorenberg, EJG Peters, PLA van Daele… - European Journal of …, 2021 - Elsevier
Abstract Importance: Among COVID-19 cases, especially the (frail) elderly show a high
number of severe infections, hospital admissions, complications, and death. The highest …

Aging & COVID-19 susceptibility, disease severity, and clinical outcomes: The role of entangled risk factors

M Farshbafnadi, SK Zonouzi, M Sabahi… - Experimental …, 2021 - Elsevier
Abstract The emergence of Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-
2) in late 2019 has been associated with a high rate of mortality and morbidity. It has been …