Preparation, characterization, and safety evaluation of poly(lactide-co-glycolide) nanoparticles for protein delivery into macrophages

AS Guedj, AJ Kell, M Barnes, S Stals… - International journal …, 2015 - Taylor & Francis
Following infection, HIV establishes reservoirs within tissues that are inaccessible to optimal
levels of antiviral drugs or within cells where HIV lies latent, thus escaping the action of anti …

PLGA based nanospheres as a potent macrophage-specific drug delivery system

B Boltnarova, J Kubackova, J Skoda, A Stefela… - Nanomaterials, 2021 - mdpi.com
Macrophages possess an innate ability to scavenge heterogenous objects from the systemic
circulation and to regulate inflammatory diseases in various organs via cytokine production …

Improving cellular uptake and cytotoxicity of chitosan-coated poly(lactic-co-glycolic acid) nanoparticles in macrophages

S Van Hees, K Elbrink, M De Schryver, PL Delputte… - …, 2020 - Taylor & Francis
Aim: This research aims to identify important formulation parameters for the enhancement of
nanoparticle (NP) uptake and decreasing the cytotoxicity in macrophages. Materials & …

Influences of surface coating of PLGA nanoparticles on immune activation of macrophages

X Chen, C Gao - Journal of Materials Chemistry B, 2018 - pubs.rsc.org
Poly (lactide-co-glycolide)(PLGA) is one of the most attractive biodegradable polymers for
loading and delivering payloads, especially in the form of nanoparticles (NPs). In this work …

Glycosaminoglycan-functionalized poly-lactide-co-glycolide nanoparticles: synthesis, characterization, cytocompatibility, and cellular uptake

SP Lamichhane, N Arya, N Ojha, E Kohler… - International Journal …, 2015 - Taylor & Francis
The efficient delivery of chemotherapeutics to the tumor via nanoparticle (NP)-based
delivery systems remains a significant challenge. This is compounded by the fact that the …

PLGA based nanoparticles for the monocyte-mediated anti-tumor drug delivery system

P Allavena, A Palmioli, R Avigni… - Journal of …, 2020 - ingentaconnect.com
Together with the development of new therapeutic agents, innovation in the delivery system
of anti-tumor drugs is required to increase tumor-specificity and avoid unexpected toxicity …

[HTML][HTML] Size-dependent cellular uptake and sustained drug release of PLGA particles

R Sun, X Liu, Y Zhang, Q Li, Y Zhu, C Fan - Particuology, 2023 - Elsevier
Abstract Poly (lactic-co-glycolic) acid (PLGA) particles have become a commonly used drug
delivery strategy in the pharmaceutical industry. In this work, we aim to investigate the size …

Nanomedical system for nucleic acid drugs created with the biodegradable nanoparticle platform

H Yamamoto, K Tahara… - Journal of …, 2012 - Taylor & Francis
Nanomedical applications of biodegradable poly (dl-lactide-co-glycolide)(PLGA)
nanoparticles (NPs) developed are discussed in this review. A surface-functionalized PLGA …

[HTML][HTML] Preferential uptake of chitosan-coated PLGA nanoparticles by primary human antigen presenting cells

V Durán, H Yasar, J Becker, D Thiyagarajan… - … , Biology and Medicine, 2019 - Elsevier
Biodegradable polymeric nanoparticles (NP) made from poly (lactid-co-glycolide) acid
(PLGA) and chitosan (CS) hold promise as innovative formulations for targeted delivery …

Dopamine-conjugated poly (lactic-co-glycolic acid) nanoparticles for protein delivery to macrophages

SY Lee, HJ Cho - Journal of colloid and interface science, 2017 - Elsevier
Poly (lactic-co-glycolic acid)-dopamine (PLGA-D)-based nanoparticles (NPs) were
developed for the delivery of protein to macrophages. PLGA-D was synthesized via amide …