Integrated analysis of DNA methylation and gene expression profiles identified S100A9 as a potential biomarker in ulcerative colitis

S Su, W Kong, J Zhang, X Wang, H Guo - Bioscience Reports, 2020 - portlandpress.com
Ulcerative colitis (UC) is a prevalent relapsing-remitting inflammatory bowel disease whose
pathogenetic mechanisms remain elusive. In the present study, colonic biopsies samples …

Identified S100A9 as a target for diagnosis and treatment of ulcerative colitis by bioinformatics analysis

L Tan, X Li, H Qin, Q Zhang, J Wang, T Chen… - Scientific Reports, 2024 - nature.com
Ulcerative colitis (UC) is a chronic, recurrent inflammatory bowel disease. UC confronts with
severe challenges including the unclear pathogenesis and lack of specific diagnostic …

DNA hypo-methylation facilitates anti-inflammatory responses in severe ulcerative colitis

H Taman, CG Fenton, E Anderssen, J Florholmen… - PLoS …, 2021 - journals.plos.org
Severe ulcerative colitis (UC) is a potentially life-threatening disease with a potential
colorectal cancer (CRC) risk. The aim of this study was to explore the relationship between …

Comprehensive DNA methylation profiling of inflammatory mucosa in ulcerative colitis

T Tahara, I Hirata, N Nakano… - Inflammatory bowel …, 2017 - academic.oup.com
Introduction Aberrant DNA methylation frequently occurs in the inflammatory mucosa in
ulcerative colitis (UC) and is involved in UC-related tumorigenesis. We performed …

A genome-wide methylation approach identifies a new hypermethylated gene panel in ulcerative colitis

K Kang, JH Bae, K Han, ES Kim, TO Kim… - International journal of …, 2016 - mdpi.com
The cause of inflammatory bowel disease (IBD) is still unknown, but there is growing
evidence that environmental factors such as epigenetic changes can contribute to the …

DNA methylation fine-tunes pro-and anti-inflammatory signalling pathways in inactive ulcerative colitis tissue biopsies

W Meng, CG Fenton, KM Johnsen, H Taman… - Scientific Reports, 2024 - nature.com
DNA methylation has been implied to play a role in the immune dysfunction associated with
inflammatory bowel disease (IBD) and the disease development of ulcerative colitis (UC) …

Novel Regulatory DNA Methylation Features of Relevance for Ulcerative Colitis: P-050

P Ruth, T Hagar, F Christopher, H Inga… - Official journal of the …, 2018 - journals.lww.com
BACKGROUND: DNA methylation is considered one of the epigenetic mechanisms believed
to play a role in the pathogenesis of ulcerative colitis (UC). The aim of this study was to …

Methylation-regulated long non-coding RNA expression in ulcerative colitis

CG Fenton, MK Ray, W Meng, RH Paulssen - International Journal of …, 2023 - mdpi.com
Long non-coding RNAs (lncRNAs) have been shown to play a role in the pathogenesis of
ulcerative colitis (UC). Although epigenetic processes such as DNA methylation and lncRNA …

Immune infiltration of ulcerative colitis and detection of the m6A subtype

C Gu, J Wu, W Zhang, Y Yao, W Yan… - Journal of …, 2022 - Wiley Online Library
Ulcerative colitis (UC) is an inflammatory bowel disease characterized by persistent colon
inflammation. N6‐methyladenosine (m6A) methylation is one of the most prevalent RNA …

RNA methylation machinery and m6A target genes as circulating biomarkers of ulcerative colitis and Crohn's disease: Correlation with disease activity, location, and …

TK Motawi, OG Shaker, G Amr, MA Senousy - Clinica Chimica Acta, 2024 - Elsevier
Accurate diagnosis of ulcerative colitis (UC) and Crohn's disease (CD), the main subtypes of
inflammatory bowel disease (IBD), has been challenging due to the constraints of the current …