Eye development is a complex and highly regulated process that consists of several
overlapping stages:(i) specification then splitting of the eye field from the developing …

Three embryonic tissue sources—the neural ectoderm, the surface ectoderm, and the
periocular mesenchyme—contribute to the formation of the mammalian eye. For this reason …

Vertebrate eye development has been an excellent model system to investigate basic
concepts of developmental biology ranging from mechanisms of tissue induction to the …

Eye Evolution: The Blurry Beginning: Current Biology Skip to Main Content Advertisement
Current Biology This journal offers authors two options (open access or subscription) to publish …

Development of the eye can be subdivided into three phases. The first phase is the
formation of the major structures of the eye by the processes of induction and regional …

We review the current knowledge of transcription factors in mammalian eye development.
The 14 transcription factors presently known to be required for eye formation are examined …

The vertebrate eye is composed of both surface ectodermal and neuroectodermal
derivatives that evaginate laterally from an epithelial anlage of the forming diencephalon …

For over a century, the vertebrate eye has served as a paradigm for organogenesis. It forms
through a complex sequence of morphogenetic events, involving the lateral evagination of …

This chapter provides an overview of the early developmental origins of six ocular tissues:
the cornea, lens, ciliary body, iris, neural retina, and retina pigment epithelium. Many of …

The mature, functional, and healthy eye is generated by the coordinated regulatory
interaction of numerous and diverse developing tissues. The neural retina of the eye must …