Chronic fatigue syndrome, the immune system and viral infection

AS Bansal, AS Bradley, KN Bishop… - Brain, behavior, and …, 2012 - Elsevier
The chronic fatigue syndrome (CFS), as defined by recent criteria, is a heterogeneous
disorder with a common set of symptoms that often either follows a viral infection or a period …

Cytokine and other immunologic markers in chronic fatigue syndrome and their relation to neuropsychological factors

R Patarca-Montero, M Antoni, MA Fletcher… - Applied …, 2001 - Taylor & Francis
The literature is reviewed and data are presented that relate to a model we have developed
to account for the perpetuation of the perplexing disorder currently termed chronic fatigue …

Is human herpesvirus-6 a trigger for chronic fatigue syndrome?

AL Komaroff - Journal of Clinical Virology, 2006 - Elsevier
Chronic fatigue syndrome (CFS) is an illness currently defined entirely by a combination of
non-specific symptoms. Despite this subjective definition, CFS is associated with objective …

Viral serologies in patients with chronic fatigue and chronic fatigue syndrome

D Buchwald, RL Ashley, T Pearlman… - Journal of medical …, 1996 - Wiley Online Library
Chronic fatigue syndrome (CFS) is an illness characterized by disabling fatigue associated
with complaints of fevers, sore throat, myalgia, lymphadenopathy, sleep disturbances …

Human herpesviruses in chronic fatigue syndrome

HL Wallace, B Natelson, W Gause… - Clinical Diagnostic …, 1999 - Am Soc Microbiol
We have conducted a double-blind study to assess the possible involvement of the human
herpesviruses (HHVs) HHV6, HHV7, Epstein-Barr virus (EBV), and cytomegalovirus in …

Stress-associated immune modulation: relevance to viral infections and chronic fatigue syndrome

R Glaser, JK Kiecolt-Glaser - The American journal of medicine, 1998 - Elsevier
The frequent The frequent association of an active viral infection with the symptoms of CFS
led researchers to hypothesize that chronic fatigue syndrome (CFS) is induced by a virus …

Chronic fatigue syndrome: inflammation, immune function, and neuroendocrine interactions

NG Klimas, AOB Koneru - Current rheumatology reports, 2007 - Springer
Investigations into the underlying cause of chronic fatigue syndrome have advanced the
field considerably in the past year. Gene microarray data have led to a better understanding …

Symptom patterns in long-duration chronic fatigue syndrome

F Friedberg, L Dechene, MJ McKenzie II… - Journal of …, 2000 - Elsevier
Objective: Our objective was to evaluate symptom patterns in patients with chronic fatigue
syndrome (CFS) who were ill for 10 or more years. Methods: This cross-sectional self-report …

Randomized clinical trial to evaluate the efficacy and safety of valganciclovir in a subset of patients with chronic fatigue syndrome

JG Montoya, AM Kogelnik, M Bhangoo… - Journal of medical …, 2013 - Wiley Online Library
There is no known treatment for chronic fatigue syndrome (CFS). Little is known about its
pathogenesis. Human herpesvirus 6 (HHV‐6) and Epstein–Barr virus (EBV) have been …

Serological and virological investigation of the role of the herpesviruses EBV, CMV and HHV‐6 in post‐infective fatigue syndrome

B Cameron, L Flamand, H Juwana… - Journal of medical …, 2010 - Wiley Online Library
Multiple previous studies have sought evidence for ongoing, active infection with, or
reactivation of, Herpesviruses in patients with chronic fatigue syndrome (CFS), with …